HOTf-catalyzed sustainable one-pot synthesis of benzene and pyridine derivatives under solvent-free conditions

Herein a versatile HOTf-catalyzed and solvent-free system for highly efficient one-pot synthesis of privileged benzene and pyridine derivatives has been developed using ketones and ketones with amines as simple substrates, respectively. The remarkable features of this green reaction include good to...

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Bibliographic Details
Published in:Green chemistry : an international journal and green chemistry resource : GC 2016-01, Vol.18 (8), p.2313-2316
Main Authors: Zhang, Xu, Wang, Zhiqiang, Xu, Kun, Feng, Yuquan, Zhao, Wei, Xu, Xuefeng, Yan, Yanlei, Yi, Wei
Format: Article
Language:English
Subjects:
Benzene
Derivatives
Ketones
Pyridines
Substrates
Sustainability
Synthesis
Tolerances
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Summary:Herein a versatile HOTf-catalyzed and solvent-free system for highly efficient one-pot synthesis of privileged benzene and pyridine derivatives has been developed using ketones and ketones with amines as simple substrates, respectively. The remarkable features of this green reaction include good to excellent yields, exclusive chemoselectivity and broad substrate/functional group tolerance. Herein a versatile HOTf-catalyzed and solvent-free system for highly efficient one-pot synthesis of privileged benzene and pyridine derivatives has been developed using ketones and ketones with amines as simple substrates, respectively.
ISSN:1463-9262
1463-9270
DOI:10.1039/c5gc02747k