Sources of Antimicrobial Resistance

The relentless rise in levels of antimicrobial resistance is an unfolding global public health crisis (1). Resistance to frontline antimicrobials such as fluoroquinolones, third- and fourth-generation cephalosporins, and carbapenems is a particular concern, as is multidrug resistance. The antimicrob...

Full description

Saved in:
Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 2013-09, Vol.341 (6153), p.1460-1461
Main Authors: Woolhouse, Mark E. J., Ward, Melissa J.
Format: Article
Language:English
Subjects:
Antibiotic resistance
Antiinfectives and antibacterials
Antimicrobial agents
Antimicrobials
Bacteria
Cattle
Cephalosporin
Drug resistance
Farms
Genetics
Human
Human populations
Humans
Livestock
Mathematical problems
Medicine
PERSPECTIVES
Public health
Salmonella
Salmonella typhimurium
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The relentless rise in levels of antimicrobial resistance is an unfolding global public health crisis (1). Resistance to frontline antimicrobials such as fluoroquinolones, third- and fourth-generation cephalosporins, and carbapenems is a particular concern, as is multidrug resistance. The antimicrobial resistance problem is not confined to human medicine: Comparable quantities of antimicrobials are used in livestock production, and resistance is rife in that setting, too, even on organic farms that restrict drug usage (2). Such observations have led to debate about whether antimicrobial resistance in farm animals is an important source of antimicrobial resistance in humans (3, 4). On page 1514 of this issue, Mather et al. (5) shed light on this important question in the context of Salmonella Typhimurium DT104 in humans and cattle in Scotland.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.1243444