Insulin-dependent diabetes and serious trauma

Purpose Trauma patients with diabetes mellitus (DM) represent a unique population as the acute injury and the underlying disease may both cause hyperglycemia that leads to poor outcomes. We investigated how insulin-dependent DM (IDDM) and noninsulin-dependent DM (NIDDM) impact mortality after seriou...

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Bibliographic Details
Published in:European journal of trauma and emergency surgery (Munich : 2007) 2016-08, Vol.42 (4), p.491-496
Main Authors: Liou, D. Z., Singer, M. B., Barmparas, G., Harada, M. Y., Mirocha, J., Bukur, M., Salim, A., Ley, E. J.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Distribution
Aged
Aged, 80 and over
Child
Critical Care Medicine
Diabetes
Diabetes Mellitus, Type 1 - complications
Diabetes Mellitus, Type 1 - drug therapy
Diabetes Mellitus, Type 1 - mortality
Diabetes Mellitus, Type 1 - physiopathology
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - drug therapy
Diabetes Mellitus, Type 2 - mortality
Diabetes Mellitus, Type 2 - physiopathology
Emergency Medicine
Female
Hospital Mortality
Humans
Hyperglycemia - complications
Hyperglycemia - drug therapy
Hyperglycemia - physiopathology
Hypoglycemic Agents - therapeutic use
Injury Severity Score
Insulin
Insulin - metabolism
Insulin - therapeutic use
Intensive
Length of Stay - statistics & numerical data
Logistic Models
Male
Medicine
Medicine & Public Health
Middle Aged
Mortality
Original Article
Prognosis
Retrospective Studies
Sports Medicine
Surgery
Surgical Orthopedics
Trauma
Traumatic Surgery
United States - epidemiology
Wounds and Injuries - complications
Wounds and Injuries - physiopathology
Young Adult
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Summary:Purpose Trauma patients with diabetes mellitus (DM) represent a unique population as the acute injury and the underlying disease may both cause hyperglycemia that leads to poor outcomes. We investigated how insulin-dependent DM (IDDM) and noninsulin-dependent DM (NIDDM) impact mortality after serious trauma without brain injury. Methods The National Trauma Data Bank (NTDB) version 7.0 was queried for all patients with moderate to severe traumatic injury [injury severity score (ISS) >9]. Patients were excluded if missing data, age 3], dead on arrival or any AIS = 6. Logistic regression modeled the association between DM and mortality as well as IDDM, NIDDM and mortality. Results Overall 166,103 trauma patients without brain injury were analyzed. Mortality was 7.6 and 4.4 % in patients with and without DM, respectively ( p  
ISSN:1863-9933
1863-9941
DOI:10.1007/s00068-015-0561-5