Aromatase inhibitors and anti-synthetase syndrome

Adjuvant therapy in postmenopausal women with endocrine-responsive breast cancer (BC) is actually centered on the use of anti-aromatase inhibitors (AI). Several reports, however, are emerging in literature associating the use of this drugs to rheumatic disorders. This case report describes the first...

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Bibliographic Details
Published in:International journal of immunopathology and pharmacology 2016, Vol.29 (3), p.494-497
Main Authors: Mascella, Fabio, Gianni, Lorenzo, Affatato, Alessandra, Fantini, Manuela
Format: Report
Language:English
Online Access:Get full text
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Summary:Adjuvant therapy in postmenopausal women with endocrine-responsive breast cancer (BC) is actually centered on the use of anti-aromatase inhibitors (AI). Several reports, however, are emerging in literature associating the use of this drugs to rheumatic disorders. This case report describes the first case of anti-synthetase syndrome diagnosis after treatment with anti-estrogen agents in a patient with pre-existing rheumatoid arthritis.
ISSN:2058-7384
DOI:10.1177/0394632016651086