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Pneumococcal conjugate vaccine herd effects on non-invasive pneumococcal pneumonia in elderly

Highlights • Herd effects of PCV's have not been well established for non-IPD pneumococcal CAP. • Cost-effectiveness analyses have been shown sensitive for assumptions on this parameter. • We assessed herd effects using a serotype specific urinary antigen test in elderly pneumococcal CAP patien...

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Bibliographic Details
Published in:Vaccine 2016-06, Vol.34 (28), p.3275-3282
Main Authors: van Werkhoven, Cornelis H, Hollingsworth, Rosalind C, Huijts, Susanne M, Bolkenbaas, Marieke, Webber, Chris, Patterson, Scott, Sanders, Elisabeth A.M, Bonten, Marc J.M
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Language:English
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Summary:Highlights • Herd effects of PCV's have not been well established for non-IPD pneumococcal CAP. • Cost-effectiveness analyses have been shown sensitive for assumptions on this parameter. • We assessed herd effects using a serotype specific urinary antigen test in elderly pneumococcal CAP patients. • We show that herd effects of non-IPD pneumococcal CAP are similar to those of IPD.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2016.05.002