New norlignans and flavonoids of Dysosma versipellis

Two new norlignans, dysosmanorlignans A and B (1-2); six new flavonoids, dysosmaflavones A-F (3-8); and 30 known compounds (9-38) were isolated from the roots of Dysosma versipellis. Their structures were determined by detailed analysis of MS and NMR spectroscopic data. Dysosmaflavones E and F both...

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Bibliographic Details
Published in:Phytochemistry letters 2016-06, Vol.16, p.75-81
Main Authors: Zheng, Yue, Xie, Yang-Guo, Zhang, Yu, Li, Tao, Li, Hui-Liang, Yan, Shi-Kai, Jin, Hui-Zi, Zhang, Wei-Dong
Format: Article
Language:English
Subjects:
Bacillus subtilis
Pseudomonas aeruginosa
Streptococcus agalactiae
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Summary:Two new norlignans, dysosmanorlignans A and B (1-2); six new flavonoids, dysosmaflavones A-F (3-8); and 30 known compounds (9-38) were isolated from the roots of Dysosma versipellis. Their structures were determined by detailed analysis of MS and NMR spectroscopic data. Dysosmaflavones E and F both exhibited mild antibacterial activities against Streptococcus agalactiae, Pseudomonas aeruginosa, and Bacillus subtilis with MIC values ranging from 93.0 to 93.8 mu g/mL.
ISSN:1874-3900
DOI:10.1016/j.phytol.2016.03.001