Effectiveness of High-dose Spironolactone Therapy in a Patient with Recurrent Protein-losing Enteropathy after the Fontan Procedure

Protein-losing enteropathy (PLE) is a rare and life-threatening complication that occurs after the Fontan procedure. We herein report the case of an 11-year-old Japanese boy who developed PLE six times after undergoing the Fontan procedure. High-dose spironolactone therapy has been effective for 2 y...

Full description

Saved in:
Bibliographic Details
Published in:Internal Medicine 2016/06/15, Vol.55(12), pp.1611-1614
Main Authors: Okano, Satomi, Sugimoto, Masaya, Takase, Masashi, Iseki, Kenichi, Kajihama, Aya, Azuma, Hiroshi
Format: Article
Language:English
Subjects:
Anti-Inflammatory Agents - therapeutic use
Child
Diuretics - therapeutic use
Fontan procedure
Fontan Procedure - adverse effects
Humans
Japan
Male
Protein-Losing Enteropathies - drug therapy
Protein-Losing Enteropathies - etiology
protein-losing enteropathy
spironolactone
Spironolactone - therapeutic use
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Protein-losing enteropathy (PLE) is a rare and life-threatening complication that occurs after the Fontan procedure. We herein report the case of an 11-year-old Japanese boy who developed PLE six times after undergoing the Fontan procedure. High-dose spironolactone therapy has been effective for 2 years. His high level of serum aldosterone decreased to a nearly normal range and spironolactone may have a diuretic and anti-inflammatory potential.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.55.6303