Uterine size and ovarian size in adolescents with functional hypothalamic amenorrhoea

IntroductionFunctional hypothalamic amenorrhoea (FHA) is a condition characterised by the absence of menses due to suppression of the hypothalamic-pituitary-ovarian axis.ObjectiveThe purpose of the study was to estimate uterine and ovarian sizes in adolescents with FHA and to compare these results w...

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Bibliographic Details
Published in:Archives of disease in childhood 2015-10, Vol.100 (10), p.948-951
Main Authors: Bumbuliene, Zana, Klimasenko, Jelena, Sragyte, Diana, Zakareviciene, Jolita, Drasutiene, Grazina
Format: Article
Language:English
Subjects:
Adolescent
Adolescents
Age
Amenorrhea
Amenorrhea - diagnostic imaging
Amenorrhea - physiopathology
Body Composition
Body Mass Index
Case-Control Studies
Child development
Eating disorders
Estradiol - blood
Exercise
Female
Females
Follicle Stimulating Hormone - blood
Gynecology
Health aspects
Humans
Immunoassay
Infertility
Lithuania
Luteinizing Hormone - blood
Measurement Techniques
Medical Evaluation
Medical Services
Menstrual Cycle
Menstruation
Ovaries
Ovary - diagnostic imaging
Ovary - physiopathology
Patients
Physical Examinations
Physiology
Prolactin - blood
Prospective Studies
Puberty
Risk factors
Scientific Concepts
Studies
Teenagers
Ultrasonography
Uterus - diagnostic imaging
Uterus - physiopathology
Youth
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Summary:IntroductionFunctional hypothalamic amenorrhoea (FHA) is a condition characterised by the absence of menses due to suppression of the hypothalamic-pituitary-ovarian axis.ObjectiveThe purpose of the study was to estimate uterine and ovarian sizes in adolescents with FHA and to compare these results with findings in peers having regular menstrual cycles.DesignProspective case-controlled study.SettingsVilnius University Hospital Santariskiu Klinikos, Lithuania.PatientsLithuanian adolescents—45 with FHA and 40 comparison group participants.Main outcome measuresWe assessed ultrasound measurements of internal reproductive organs, levels of luteinising hormone, follicle-stimulating hormone, prolactin, oestradiol and calculated body mass index (BMI).ResultsThe mean age of the participants was 16.3±1.2 years, the mean age after menarche—3.6 years. In adolescents with FHA the BMI was 17.8±1.8 kg/m2 and 20.4±1.4 kg/m2 in the comparison group, p
ISSN:0003-9888
1468-2044
DOI:10.1136/archdischild-2014-307504