Oncogene-mediated mouse pancreatic progenitor cells show cancer stem cell phenotype

In vivo, CD133+ cells showed tumorigenicity, which was dependent on the transplanted cell number. [...]GFP+ cells in tumor consisted of CD133+ cells and CD133- cells by immunostaining, suggesting that CD133+ cancer cells could form a heterogeneous tumor.

Saved in:
Bibliographic Details
Published in:Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2016-08, Vol.16 (4), p.S143-S143
Main Authors: Ise, Yuuki, Shimizu, Kazuya, Uenoyama, Kyohei, Nishiyama, Satoshi, Tsuchida, Yuka, Hori, Yuichi
Format: Article
Language:English
Subjects:
Cancer
Endocrinology & Metabolism
Gastroenterology and Hepatology
Stem cells
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In vivo, CD133+ cells showed tumorigenicity, which was dependent on the transplanted cell number. [...]GFP+ cells in tumor consisted of CD133+ cells and CD133- cells by immunostaining, suggesting that CD133+ cancer cells could form a heterogeneous tumor.
ISSN:1424-3903
1424-3911
DOI:10.1016/j.pan.2016.06.514