PO-0634Factors Limiting Usefulness Of Serum And Urinary Ngal As A Marker Of Acute Kidney Injury In Preterm Newborns

Background and aimsNeutrophile gelatinase-associated lipocaline (NGAL) is postulated to be a highly sensitive and specific marker of acute kidney injury (AKI). The aim of this study was to assess the factors affecting serum and urine total NGAL in preterm newborns, limiting the role of this new pote...

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Bibliographic Details
Published in:Archives of disease in childhood 2014-10, Vol.99 (Suppl 2), p.A461-A461
Main Authors: Suchojad, A, Smertka, M, Tarko, A, Majcherczyk, M, Brzozowska, A, Wroblewska, J, Maruniak-Chudek, I
Format: Article
Language:English
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Summary:Background and aimsNeutrophile gelatinase-associated lipocaline (NGAL) is postulated to be a highly sensitive and specific marker of acute kidney injury (AKI). The aim of this study was to assess the factors affecting serum and urine total NGAL in preterm newborns, limiting the role of this new potential marker of AKI.MethodsSerum and urinary total NGAL concentrations were determined in 57 admitted to the Neonatal Intensive Care Unit preterm infants in the following points of time: first week of life, between 8 and 14 day of life, and after the fourth week of life. Patients' clinical condition was evaluated based on NTISS (Neonatal Therapeutic Intervention Scoring System). Two gestational age subgroups were distinguished:
ISSN:0003-9888
DOI:10.1136/archdischild-2014-307384.1276