PO-0696Baseline Coagulation Times Do Not Influence Likelihood Of Intraventricular Haemorrhage (ivh) In Extremely Premature Neonates

BackgroundDerangements of haemostasis are implicated in IVH. Prothrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen level are frequently monitored in premature infants. Neonates frequently receive frozen plasma (FP) in attempt to correct perceived haemostatic abnormalitie...

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Bibliographic Details
Published in:Archives of disease in childhood 2014-10, Vol.99 (Suppl 2), p.A482-A482
Main Authors: Neary, E, Ni Ainle, F, Cotter, M, McCallion, N
Format: Article
Language:English
Online Access:Get full text
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Summary:BackgroundDerangements of haemostasis are implicated in IVH. Prothrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen level are frequently monitored in premature infants. Neonates frequently receive frozen plasma (FP) in attempt to correct perceived haemostatic abnormalities based on laboratory results.MethodsProspective observational study was performed. Blood was drawn into citrated tubes from neonates (100 s. In this subgroup; IVH rates in those that received FP (n = 17) vs. those that did not (n = 4) was not significantly different (p = 0.447). There was no significant difference in IVH development in high risk (APTT >100 s, Administered FP) vs. low risk infants (APTT
ISSN:0003-9888
DOI:10.1136/archdischild-2014-307384.1335