Effects of bacteriophages on biofilm formation by strains of Pseudomonas aeruginosa

The effects of two Pseudomonas aeruginosa bacteriophages, vB-Pa 4 and vB-Pa 5, on the formation and development of biofilms of six polyresistant hospital strains of P. aeruginosa have been investigated. Pretreatment of bacteriophages prevented the formation or almost completely prevented the growth...

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Bibliographic Details
Published in:Applied biochemistry and microbiology 2016-05, Vol.52 (3), p.293-297
Main Authors: Gabisoniya, T. G., Loladze, M. Zh, Nadiradze, M. M., Chakhunashvili, N. K., Alibegashvili, M. G., Tamarashvili, N. G., Pushkina, V. A.
Format: Article
Language:English
Subjects:
Antibiotics
Bacteria
Biochemistry
Biofilms
Biomedical and Life Sciences
Drug resistance
Life Sciences
Medical Microbiology
Microbiology
Pseudomonas aeruginosa
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Summary:The effects of two Pseudomonas aeruginosa bacteriophages, vB-Pa 4 and vB-Pa 5, on the formation and development of biofilms of six polyresistant hospital strains of P. aeruginosa have been investigated. Pretreatment of bacteriophages prevented the formation or almost completely prevented the growth of adequate biofilms. The biofilms that had already formed were partially or completely destroyed after phage treatment. The results demonstrate the prospects of using isolated bacteriophages of P. aeruginosa to destroy biofilms and prevent their formation.
ISSN:0003-6838
1608-3024
DOI:10.1134/S0003683816030042