Base of tongue squamous cell carcinoma with infiltrative bone marrow carcinomatosis after definitive chemoradiation: A case report

Background Oropharyngeal squamous cell carcinoma (SCC) is known for its propensity for aggressive local progression and regional lymphatic spread. Distant metastases are relatively uncommon and the likelihood of hematogenous dissemination is primarily related to the extent and location of cervical l...

Full description

Saved in:
Bibliographic Details
Published in:Head & neck 2016-07, Vol.38 (7), p.E2449-E2453
Main Authors: Christopherson, Kaitlin, Reisman, David N., Fredenburg, Kristianna, DeJesus, Reordan, Mendenhall, William M., Andersen, Peter
Format: Article
Language:English
Subjects:
base of tongue
carcinomatosis
case report
definitive chemoradiation
squamous cell carcinoma
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c3195-a18ee05bc3ea1a2e329f509fac0de62f1d99d6050320475a966eeb2da771c5e3
cites
container_end_page E2453
container_issue 7
container_start_page E2449
container_title Head & neck
container_volume 38
creator Christopherson, Kaitlin
Reisman, David N.
Fredenburg, Kristianna
DeJesus, Reordan
Mendenhall, William M.
Andersen, Peter
description Background Oropharyngeal squamous cell carcinoma (SCC) is known for its propensity for aggressive local progression and regional lymphatic spread. Distant metastases are relatively uncommon and the likelihood of hematogenous dissemination is primarily related to the extent and location of cervical lymph node metastases. Common sites of distant metastasis include the liver and lung. Methods We report an unusual case of base of tongue SCC with infiltrative bone marrow carcinomatosis presenting months after definitive chemoradiation despite locoregional control. Results Our patient exhibited an unusual pattern of distant dissemination after definitive chemoradiation had resulted in locoregional control. Conclusion Patients who present with bone marrow failure after definitive treatment with apparent disease control should be monitored for bone marrow infiltration by the tumor and, if such infiltration is present, should be evaluated for palliative chemotherapy. Unfortunately, the prognosis for such patients is poor. © 2016 Wiley Periodicals, Inc. Head Neck 38: E2449–E2453, 2016
doi_str_mv 10.1002/hed.24155
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1808676309</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1808676309</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3195-a18ee05bc3ea1a2e329f509fac0de62f1d99d6050320475a966eeb2da771c5e3</originalsourceid><addsrcrecordid>eNpdkblOxDAQhi0E4i54AWSJhiYwtmN7TccNEhINveVNJqxREi92woqWJ8e7XBLV_NJ8c_6EHDA4YQD8dIb1CS-ZlGtkm4HRBYhSry91KQoButwiOym9AIBQJd8kW1xBCZLBNvm4cAlpaOgQ-ucRaXodXRfGRCtsW1q5WPk-dI4u_DCjvm98O0Q3-Dek09Aj7VyMYfHHDSH5RF0zYKQ1Nr73K7aaYReiq30uDf0ZPc8VeWzEeYjDHtloXJtw_zvukqeb66fLu-Lh8fb-8vyhqAQzsnBsgghyWgl0zHEU3DQSTOMqqFHxhtXG1AokCA6lls4ohTjltdOaVRLFLjn-ajuP4XXENNjOp-WVrsd8sGUTmCitBJiMHv1DX8IY-7ycZdqUeqK5WlKH39Q47bC28-jzO97tz3MzcPoFLHyL7795Bnbpms2u2ZVr9u76aiXEJ8riizs</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1794787269</pqid></control><display><type>article</type><title>Base of tongue squamous cell carcinoma with infiltrative bone marrow carcinomatosis after definitive chemoradiation: A case report</title><source>Wiley-Blackwell Read &amp; Publish Collection</source><creator>Christopherson, Kaitlin ; Reisman, David N. ; Fredenburg, Kristianna ; DeJesus, Reordan ; Mendenhall, William M. ; Andersen, Peter</creator><creatorcontrib>Christopherson, Kaitlin ; Reisman, David N. ; Fredenburg, Kristianna ; DeJesus, Reordan ; Mendenhall, William M. ; Andersen, Peter</creatorcontrib><description>Background Oropharyngeal squamous cell carcinoma (SCC) is known for its propensity for aggressive local progression and regional lymphatic spread. Distant metastases are relatively uncommon and the likelihood of hematogenous dissemination is primarily related to the extent and location of cervical lymph node metastases. Common sites of distant metastasis include the liver and lung. Methods We report an unusual case of base of tongue SCC with infiltrative bone marrow carcinomatosis presenting months after definitive chemoradiation despite locoregional control. Results Our patient exhibited an unusual pattern of distant dissemination after definitive chemoradiation had resulted in locoregional control. Conclusion Patients who present with bone marrow failure after definitive treatment with apparent disease control should be monitored for bone marrow infiltration by the tumor and, if such infiltration is present, should be evaluated for palliative chemotherapy. Unfortunately, the prognosis for such patients is poor. © 2016 Wiley Periodicals, Inc. Head Neck 38: E2449–E2453, 2016</description><identifier>ISSN: 1043-3074</identifier><identifier>EISSN: 1097-0347</identifier><identifier>DOI: 10.1002/hed.24155</identifier><identifier>PMID: 26040510</identifier><identifier>CODEN: HEANEE</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>base of tongue ; carcinomatosis ; case report ; definitive chemoradiation ; squamous cell carcinoma</subject><ispartof>Head &amp; neck, 2016-07, Vol.38 (7), p.E2449-E2453</ispartof><rights>2015 Wiley Periodicals, Inc.</rights><rights>2016 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3195-a18ee05bc3ea1a2e329f509fac0de62f1d99d6050320475a966eeb2da771c5e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26040510$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Christopherson, Kaitlin</creatorcontrib><creatorcontrib>Reisman, David N.</creatorcontrib><creatorcontrib>Fredenburg, Kristianna</creatorcontrib><creatorcontrib>DeJesus, Reordan</creatorcontrib><creatorcontrib>Mendenhall, William M.</creatorcontrib><creatorcontrib>Andersen, Peter</creatorcontrib><title>Base of tongue squamous cell carcinoma with infiltrative bone marrow carcinomatosis after definitive chemoradiation: A case report</title><title>Head &amp; neck</title><addtitle>Head Neck</addtitle><description>Background Oropharyngeal squamous cell carcinoma (SCC) is known for its propensity for aggressive local progression and regional lymphatic spread. Distant metastases are relatively uncommon and the likelihood of hematogenous dissemination is primarily related to the extent and location of cervical lymph node metastases. Common sites of distant metastasis include the liver and lung. Methods We report an unusual case of base of tongue SCC with infiltrative bone marrow carcinomatosis presenting months after definitive chemoradiation despite locoregional control. Results Our patient exhibited an unusual pattern of distant dissemination after definitive chemoradiation had resulted in locoregional control. Conclusion Patients who present with bone marrow failure after definitive treatment with apparent disease control should be monitored for bone marrow infiltration by the tumor and, if such infiltration is present, should be evaluated for palliative chemotherapy. Unfortunately, the prognosis for such patients is poor. © 2016 Wiley Periodicals, Inc. Head Neck 38: E2449–E2453, 2016</description><subject>base of tongue</subject><subject>carcinomatosis</subject><subject>case report</subject><subject>definitive chemoradiation</subject><subject>squamous cell carcinoma</subject><issn>1043-3074</issn><issn>1097-0347</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNpdkblOxDAQhi0E4i54AWSJhiYwtmN7TccNEhINveVNJqxREi92woqWJ8e7XBLV_NJ8c_6EHDA4YQD8dIb1CS-ZlGtkm4HRBYhSry91KQoButwiOym9AIBQJd8kW1xBCZLBNvm4cAlpaOgQ-ucRaXodXRfGRCtsW1q5WPk-dI4u_DCjvm98O0Q3-Dek09Aj7VyMYfHHDSH5RF0zYKQ1Nr73K7aaYReiq30uDf0ZPc8VeWzEeYjDHtloXJtw_zvukqeb66fLu-Lh8fb-8vyhqAQzsnBsgghyWgl0zHEU3DQSTOMqqFHxhtXG1AokCA6lls4ohTjltdOaVRLFLjn-ajuP4XXENNjOp-WVrsd8sGUTmCitBJiMHv1DX8IY-7ycZdqUeqK5WlKH39Q47bC28-jzO97tz3MzcPoFLHyL7795Bnbpms2u2ZVr9u76aiXEJ8riizs</recordid><startdate>201607</startdate><enddate>201607</enddate><creator>Christopherson, Kaitlin</creator><creator>Reisman, David N.</creator><creator>Fredenburg, Kristianna</creator><creator>DeJesus, Reordan</creator><creator>Mendenhall, William M.</creator><creator>Andersen, Peter</creator><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>7QP</scope><scope>7TK</scope><scope>K9.</scope></search><sort><creationdate>201607</creationdate><title>Base of tongue squamous cell carcinoma with infiltrative bone marrow carcinomatosis after definitive chemoradiation: A case report</title><author>Christopherson, Kaitlin ; Reisman, David N. ; Fredenburg, Kristianna ; DeJesus, Reordan ; Mendenhall, William M. ; Andersen, Peter</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3195-a18ee05bc3ea1a2e329f509fac0de62f1d99d6050320475a966eeb2da771c5e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>base of tongue</topic><topic>carcinomatosis</topic><topic>case report</topic><topic>definitive chemoradiation</topic><topic>squamous cell carcinoma</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Christopherson, Kaitlin</creatorcontrib><creatorcontrib>Reisman, David N.</creatorcontrib><creatorcontrib>Fredenburg, Kristianna</creatorcontrib><creatorcontrib>DeJesus, Reordan</creatorcontrib><creatorcontrib>Mendenhall, William M.</creatorcontrib><creatorcontrib>Andersen, Peter</creatorcontrib><collection>PubMed</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><jtitle>Head &amp; neck</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Christopherson, Kaitlin</au><au>Reisman, David N.</au><au>Fredenburg, Kristianna</au><au>DeJesus, Reordan</au><au>Mendenhall, William M.</au><au>Andersen, Peter</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Base of tongue squamous cell carcinoma with infiltrative bone marrow carcinomatosis after definitive chemoradiation: A case report</atitle><jtitle>Head &amp; neck</jtitle><addtitle>Head Neck</addtitle><date>2016-07</date><risdate>2016</risdate><volume>38</volume><issue>7</issue><spage>E2449</spage><epage>E2453</epage><pages>E2449-E2453</pages><issn>1043-3074</issn><eissn>1097-0347</eissn><coden>HEANEE</coden><abstract>Background Oropharyngeal squamous cell carcinoma (SCC) is known for its propensity for aggressive local progression and regional lymphatic spread. Distant metastases are relatively uncommon and the likelihood of hematogenous dissemination is primarily related to the extent and location of cervical lymph node metastases. Common sites of distant metastasis include the liver and lung. Methods We report an unusual case of base of tongue SCC with infiltrative bone marrow carcinomatosis presenting months after definitive chemoradiation despite locoregional control. Results Our patient exhibited an unusual pattern of distant dissemination after definitive chemoradiation had resulted in locoregional control. Conclusion Patients who present with bone marrow failure after definitive treatment with apparent disease control should be monitored for bone marrow infiltration by the tumor and, if such infiltration is present, should be evaluated for palliative chemotherapy. Unfortunately, the prognosis for such patients is poor. © 2016 Wiley Periodicals, Inc. Head Neck 38: E2449–E2453, 2016</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>26040510</pmid><doi>10.1002/hed.24155</doi><tpages>5</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1043-3074
ispartof Head & neck, 2016-07, Vol.38 (7), p.E2449-E2453
issn 1043-3074
1097-0347
language eng
recordid cdi_proquest_miscellaneous_1808676309
source Wiley-Blackwell Read & Publish Collection
subjects base of tongue
carcinomatosis
case report
definitive chemoradiation
squamous cell carcinoma
title Base of tongue squamous cell carcinoma with infiltrative bone marrow carcinomatosis after definitive chemoradiation: A case report
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T17%3A11%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Base%20of%20tongue%20squamous%20cell%20carcinoma%20with%20infiltrative%20bone%20marrow%20carcinomatosis%20after%20definitive%20chemoradiation:%20A%20case%20report&rft.jtitle=Head%20&%20neck&rft.au=Christopherson,%20Kaitlin&rft.date=2016-07&rft.volume=38&rft.issue=7&rft.spage=E2449&rft.epage=E2453&rft.pages=E2449-E2453&rft.issn=1043-3074&rft.eissn=1097-0347&rft.coden=HEANEE&rft_id=info:doi/10.1002/hed.24155&rft_dat=%3Cproquest_pubme%3E1808676309%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c3195-a18ee05bc3ea1a2e329f509fac0de62f1d99d6050320475a966eeb2da771c5e3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1794787269&rft_id=info:pmid/26040510&rfr_iscdi=true