The histological variants of liposarcoma: predictive MRI findings with prognostic implications, management, follow-up, and differential diagnosis

Liposarcoma is the single most common soft tissue sarcoma accounting for up to 35 % of sarcomas. It represents a histologically diverse group of soft tissue tumors that demonstrate a wide range of imaging appearances with varied behavior patterns. Correspondingly, more aggressive histological subtyp...

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Bibliographic Details
Published in:Skeletal radiology 2016-09, Vol.45 (9), p.1193-1204
Main Authors: Rizer, Magda, Singer, Adam D., Edgar, Mark, Jose, Jean, Subhawong, Ty K.
Format: Article
Language:English
Subjects:
Diagnosis
Diagnosis, Differential
Follow-Up Studies
Humans
Imaging
Liposarcoma - diagnosis
Liposarcoma - pathology
Liposarcoma - therapy
Magnetic Resonance Imaging
Medicine
Medicine & Public Health
Nuclear Medicine
Orthopedics
Pathology
Prognosis
Radiology
Radiotherapy
Review Article
Sarcoma
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Summary:Liposarcoma is the single most common soft tissue sarcoma accounting for up to 35 % of sarcomas. It represents a histologically diverse group of soft tissue tumors that demonstrate a wide range of imaging appearances with varied behavior patterns. Correspondingly, more aggressive histological subtypes often require management that includes a combination of surgery, chemotherapy, and radiation therapy. Distinguishing among liposarcoma subtypes has important therapeutic and prognostic implications. In this manuscript, we review the liposarcoma subtypes and their histologic and MRI findings, prognostic implications, and differential diagnostic considerations.
ISSN:0364-2348
1432-2161
DOI:10.1007/s00256-016-2409-4