Development of tumor selection on the basis of pathological staging in clinically localized prostate carcinoma

Four hundred and eighty-eight radical retropubic prostatectomies (RRP) were performed on clinically localized prostate cancer at one institution within 5 years (1992-1996). These were then analyzed regarding the migration of pathological tumor stages towards more localized stages. Within the observa...

Full description

Saved in:
Bibliographic Details
Published in:Urologe. Ausgabe A 1998-03, Vol.37 (2), p.195-198
Main Authors: Noldus, J., Graefen, M., Hammerer, P., Henke, R.-P., Huland, H.
Format: Article
Language:English
Subjects:
Prostate cancer
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Four hundred and eighty-eight radical retropubic prostatectomies (RRP) were performed on clinically localized prostate cancer at one institution within 5 years (1992-1996). These were then analyzed regarding the migration of pathological tumor stages towards more localized stages. Within the observation period, the annual rate of RRP increased by 81 % from 69 to 125 cases. The authors noted a decline in the occurrence of advanced tumor stages (65.0 % to 39.2 %) and small cancers ( < 0.5 cc: 7.2 % to 1.6 %) and an increase in pathological T2 tumors (30.4 % to 55.2 %). The rate of positive surgical margins declined from 34.7 % to 12.8 % (for all pathological stages). These data confirm trends which were observed in the USA with increasing detection and treatment of localized prostate cancer.[PUBLICATION ABSTRACT]
ISSN:0340-2592
1433-0563
DOI:10.1007/s001200050173