Development of tumor selection on the basis of pathological staging in clinically localized prostate carcinoma

Four hundred and eighty-eight radical retropubic prostatectomies (RRP) were performed on clinically localized prostate cancer at one institution within 5 years (1992-1996). These were then analyzed regarding the migration of pathological tumor stages towards more localized stages. Within the observa...

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Published in:Urologe. Ausgabe A 1998-03, Vol.37 (2), p.195-198
Main Authors: Noldus, J., Graefen, M., Hammerer, P., Henke, R.-P., Huland, H.
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Language:English
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Prostate cancer
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container_title Urologe. Ausgabe A
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creator Noldus, J.
Graefen, M.
Hammerer, P.
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Huland, H.
description Four hundred and eighty-eight radical retropubic prostatectomies (RRP) were performed on clinically localized prostate cancer at one institution within 5 years (1992-1996). These were then analyzed regarding the migration of pathological tumor stages towards more localized stages. Within the observation period, the annual rate of RRP increased by 81 % from 69 to 125 cases. The authors noted a decline in the occurrence of advanced tumor stages (65.0 % to 39.2 %) and small cancers ( < 0.5 cc: 7.2 % to 1.6 %) and an increase in pathological T2 tumors (30.4 % to 55.2 %). The rate of positive surgical margins declined from 34.7 % to 12.8 % (for all pathological stages). These data confirm trends which were observed in the USA with increasing detection and treatment of localized prostate cancer.[PUBLICATION ABSTRACT]
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title Development of tumor selection on the basis of pathological staging in clinically localized prostate carcinoma
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