Relevance of and New Developments in Serology for Toxoplasmosis

Toxoplasmosis is a widespread parasitic disease caused by the intracellular parasite Toxoplasma gondii with a wide spectrum of clinical outcomes. The biological diagnosis of toxoplasmosis is often difficult and of paramount importance because clinical features are not sufficient to discriminate betw...

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Bibliographic Details
Published in:Trends in parasitology 2016-06, Vol.32 (6), p.492-506
Main Authors: Dard, Céline, Fricker-Hidalgo, Hélène, Brenier-Pinchart, Marie-Pierre, Pelloux, Hervé
Format: Article
Language:English
Subjects:
Animals
Antibodies, Protozoan - blood
Diagnosis, Differential
Gastroenterology and Hepatology
Humans
Infectious Disease
recombinant antigens
Serologic Tests - standards
Serologic Tests - trends
serology
serotyping
Toxoplasma - immunology
Toxoplasma gondii
toxoplasmosis
Toxoplasmosis - blood
Toxoplasmosis - diagnosis
Toxoplasmosis - parasitology
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Summary:Toxoplasmosis is a widespread parasitic disease caused by the intracellular parasite Toxoplasma gondii with a wide spectrum of clinical outcomes. The biological diagnosis of toxoplasmosis is often difficult and of paramount importance because clinical features are not sufficient to discriminate between toxoplasmosis and other illnesses. Serological tests are the most widely used biological tools for the diagnosis of toxoplasmosis worldwide. This review focuses on the crucial role of serology in providing answers to the most important questions related to the epidemiology and diagnosis of toxoplasmosis in human pathology. Notwithstanding their undeniable importance, serological tools need to be continuously improved and the interpretation of the ensuing results remains complex in many circumstances.
ISSN:1471-4922
1471-5007
DOI:10.1016/j.pt.2016.04.001