Nutraceuticals for body-weight management: The role of green tea catechins

Abstract Green tea catechins mixed with caffeine have been proposed as adjuvants for maintaining or enhancing energy expenditure and for increasing fat oxidation, in the context of prevention and treatment of obesity. These catechins-caffeine mixtures seem to counteract the decrease in metabolic rat...

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Bibliographic Details
Published in:Physiology & behavior 2016-08, Vol.162, p.83-87
Main Authors: Janssens, Pilou L.H.R, Hursel, Rick, Westerterp-Plantenga, Margriet S
Format: Article
Language:English
Subjects:
Animals
Body Weight - drug effects
Body Weight - genetics
Body-weight maintenance
Caffeine - pharmacology
Catechin - administration & dosage
Catechol O-Methyltransferase - genetics
Central Nervous System Stimulants - pharmacology
Dietary Supplements
Energy expenditure
Fat absorption
Fat oxidation
Fats - metabolism
Gastrointestinal Microbiome - physiology
Genetic predisposition
Gut microbiota
Humans
Polymorphism, Single Nucleotide - genetics
Psychiatry
Tea - chemistry
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Summary:Abstract Green tea catechins mixed with caffeine have been proposed as adjuvants for maintaining or enhancing energy expenditure and for increasing fat oxidation, in the context of prevention and treatment of obesity. These catechins-caffeine mixtures seem to counteract the decrease in metabolic rate that occurs during weight loss. Their effects are of particular importance during weight maintenance after weight loss. Other metabolic targets may be fat absorption and the gut microbiota composition, but these effects still need further investigation in combination with weight loss. Limitations for the effects of green tea catechins are moderating factors such as genetic predisposition related to COMT-activity, habitual caffeine intake, and ingestion combined with dietary protein. In conclusion, a mixture of green tea catechins and caffeine has a beneficial effect on body-weight management, especially by sustained energy expenditure, fat oxidation, and preservation of fat free body-mass, after energy restriction induced body-weight loss, when taking the limitations into account.
ISSN:0031-9384
1873-507X
DOI:10.1016/j.physbeh.2016.01.044