Suspected acute myocardial infarction in a dystrophin-deficient dog

Highlights • Golden retriever muscular dystrophy (GRMD) is a model for Duchenne muscular dystrophy (DMD). • Both DMD and GRMD cause predominantly skeletal muscle disease but cardiac involvement is seen. • Cardiac disease in DMD and GRMD generally expresses as progressive cardiomyopathy. • Cases of a...

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Bibliographic Details
Published in:Neuromuscular disorders : NMD 2016-06, Vol.26 (6), p.361-366
Main Authors: Schneider, Sarah Morar, DVM, Coleman, Amanda Erickson, DVM, Guo, Lee-Jae, DVM, MS, Tou, Sandra, DVM, Keene, Bruce W., DVM, MSc, Kornegay, Joe N., DVM, PhD
Format: Article
Language:English
Subjects:
Animal model
Animals
Biomarkers - blood
Cardiomyopathy
Dog Diseases - diagnosis
Dog Diseases - genetics
Dog Diseases - physiopathology
Dogs
Duchenne muscular dystrophy
Fatal Outcome
Female
Golden retriever muscular dystrophy
Heart - diagnostic imaging
Heart - physiopathology
Muscular dystrophy
Muscular Dystrophy, Animal - complications
Muscular Dystrophy, Animal - diagnosis
Muscular Dystrophy, Animal - genetics
Muscular Dystrophy, Animal - physiopathology
Myocardial infarction
Myocardial Infarction - complications
Myocardial Infarction - diagnostic imaging
Myocardial Infarction - physiopathology
Myocardial Infarction - veterinary
Myocardium - pathology
Neurology
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Summary:Highlights • Golden retriever muscular dystrophy (GRMD) is a model for Duchenne muscular dystrophy (DMD). • Both DMD and GRMD cause predominantly skeletal muscle disease but cardiac involvement is seen. • Cardiac disease in DMD and GRMD generally expresses as progressive cardiomyopathy. • Cases of acute cardiac disease compatible with myocardial infarction have been reported in DMD. • A GRMD dog with acute cardiac disease consistent with myocardial infarction is reported.
ISSN:0960-8966
1873-2364
DOI:10.1016/j.nmd.2016.02.005