Serum sTREM-1 level is quite higher in Crimean Congo Hemorrhagic Fever, a viral infection

Members of triggering receptor expressed on myeloid cells (TREM) family are known as immunmodulators in several infectious or noninfectious inflammatory disorders. The information about their role in viral infections is very limited. To enlighten if there is a relation between soluble TREM‐1(sTREM‐1...

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Bibliographic Details
Published in:Journal of medical virology 2016-09, Vol.88 (9), p.1473-1478
Main Authors: Altay, Fatma Aybala, Elaldi, Nazif, Şentürk, Gönül Çiçek, Altin, Nilgün, Gözel, Mustafa Gökhan, Albayrak, Yurdagül, Şencan, İrfan
Format: Article
Language:English
Subjects:
Adult
CCHF
Female
Fever
Hemorrhagic Fever Virus, Crimean-Congo - immunology
Hemorrhagic Fever Virus, Crimean-Congo - isolation & purification
Hemorrhagic Fever, Crimean - blood
Hemorrhagic Fever, Crimean - immunology
Hemorrhagic Fever, Crimean - virology
Humans
Inflammation
Male
Membrane Glycoproteins - blood
Middle Aged
Receptors, Immunologic - blood
sTREM-1
Triggering Receptor Expressed on Myeloid Cells-1
viral infection
Viral infections
Virology
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Summary:Members of triggering receptor expressed on myeloid cells (TREM) family are known as immunmodulators in several infectious or noninfectious inflammatory disorders. The information about their role in viral infections is very limited. To enlighten if there is a relation between soluble TREM‐1(sTREM‐1) and a viral infection, Crimean Congo Haemorrhagic Fever (CCHF), we investigated the levels of sTREM‐1 in the sera of 39 CCHF patients both at admission and at recovery and compared with 40 healthy controls by using microELISA technique. Statistical analysis was made by using Statistical Package for Social Sciences (SPSS) for Windows 20 programme. Value of P 
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.24496