Rectal mucosa metastasis in recurrent prostate cancer : (68)Ga-PSMA-PET/CT allows targeted salvage radiotherapy

This article presents for the first time a case of rectal mucosa metastasis of recurrent prostate cancer that was diagnosed with (68)Ga-PSMA PET/CT. After histological confirmation, the patient was treated with salvage radiotherapy. This case report underlines the specificity and efficacy of PSMA-ba...

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Bibliographic Details
Published in:Urologe. Ausgabe A 2016-08, Vol.55 (8), p.1086-1088
Main Authors: Düwel, C, Blümel, C, Westenfelder, K, Wagner-Thiessen, E, Becker, A, Gschwend, J E, Eiber, M, Maurer, T
Format: Article
Language:ger
Subjects:
Edetic Acid - analogs & derivatives
Humans
Intestinal Mucosa - diagnostic imaging
Intestinal Mucosa - radiation effects
Male
Middle Aged
Neoplasm Recurrence, Local - diagnostic imaging
Neoplasm Recurrence, Local - radiotherapy
Oligopeptides
Positron Emission Tomography Computed Tomography - methods
Radiopharmaceuticals
Radiotherapy, Image-Guided - methods
Rectal Neoplasms - diagnostic imaging
Rectal Neoplasms - radiotherapy
Rectal Neoplasms - secondary
Salvage Therapy - methods
Treatment Outcome
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Summary:This article presents for the first time a case of rectal mucosa metastasis of recurrent prostate cancer that was diagnosed with (68)Ga-PSMA PET/CT. After histological confirmation, the patient was treated with salvage radiotherapy. This case report underlines the specificity and efficacy of PSMA-based PET imaging. In case of biochemical relapse, it can be used even at low PSA levels to detect prostate cancer metastases that might also be in atypical locations. Thus, (68)Ga-PSMA PET/CT may allow new options for salvage therapy.
ISSN:1433-0563
DOI:10.1007/s00120-016-0169-3