Antimutagenic effect of heteroxylans, arabinogalactans, pectins and mannans in the Euglena assay

A series of plant cell wall polysaccharides - heteroxylans, arabinogalactans, pectins and mannans exerted antimutagenic (antibleaching) activity against acridine orange- and ofloxacin-induced mutagenicity in the Euglena assay. All polysaccharides tested exhibited a significant dose-dependent antible...

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Bibliographic Details
Published in:World journal of microbiology & biotechnology 2001-04, Vol.17 (3), p.293-299
Main Authors: BELICOVA, A, EBRINGER, L, KRAJCOVIC, J, HROMADKOVA, Z, EBRINGEROVA, A
Format: Article
Language:English
Subjects:
arabinogalactan
arabinogalactans
Bacteria
Biological and medical sciences
Biotechnology
Euglena
Freshwater
Fundamental and applied biological sciences. Psychology
Health. Pharmaceutical industry
heteroxylans
Industrial applications and implications. Economical aspects
mannan
Mode of action
Mutagenicity
Mutagens
Other active biomolecules
pectin
Production of active biomolecules
Saccharides
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Summary:A series of plant cell wall polysaccharides - heteroxylans, arabinogalactans, pectins and mannans exerted antimutagenic (antibleaching) activity against acridine orange- and ofloxacin-induced mutagenicity in the Euglena assay. All polysaccharides tested exhibited a significant dose-dependent antibleaching activity and the percentage inhibition of mutagenicity ranged from 52 to 96%. It can be assumed that the antimutagenicity of the polysaccharides depends on their structural and compositional properties as well as on the different mode of action of both the mutagens tested.[PUBLICATION ABSTRACT]
ISSN:0959-3993
1573-0972
DOI:10.1023/A:1016676401954