Medical treatment of stable angina: A tailored therapeutic approach

Abstract Treatment of stable angina is often challenging. In spite of several therapeutic approaches, many of these patients still have symptoms, which inevitably affect their daily activity and quality of life. Current ESC guidelines suggest an algorithm for the medical treatment of stable angina c...

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Bibliographic Details
Published in:International journal of cardiology 2016-10, Vol.220, p.445-453
Main Authors: Manolis, Athanasios J, Poulimenos, Leonidas E, Ambrosio, Giuseppe, Kallistratos, Manolis S, Lopez-Sendon, Jose, Dechend, Ralf, Mancia, Giuseppe, Camm, John
Format: Article
Language:English
Subjects:
Adrenergic beta-Antagonists - therapeutic use
Angina drugs
Angina, Stable - diagnosis
Angina, Stable - drug therapy
Calcium Channel Blockers - therapeutic use
Cardiotonic Agents - therapeutic use
Cardiovascular
Humans
Prognosis
Randomized Controlled Trials as Topic - methods
Stable angina
Symptom relief
Treatment Outcome
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Summary:Abstract Treatment of stable angina is often challenging. In spite of several therapeutic approaches, many of these patients still have symptoms, which inevitably affect their daily activity and quality of life. Current ESC guidelines suggest an algorithm for the medical treatment of stable angina categorizing antianginal drugs as first- or second-line therapy, and then providing little suggestions to guide choice within each step. However, several questions emerge: Is there evidence for such an approach? Is there a true difference between first and second-line drugs in terms of prognosis and symptom relief? Is it possible to individualize patients and tailor treatment according to their comorbidities or risk factors? The purpose of this review is to summarize the evidence behind stable angina treatment recommendations, and to suggest a systematic therapeutic approach tailored to patients’ cardiovascular profile, risk factors, and comorbidities.
ISSN:0167-5273
1874-1754
DOI:10.1016/j.ijcard.2016.06.150