Investigation into the cytotoxicity and mutagenicity of the Marajó Archipelago waters using Plagioscion squamosissimus (Perciformes: Sciaenidae) as a bioindicator

Maintaining water quality within tolerable limits is a basic need of the riverside communities in the Amazon. Using endemic aquatic organisms as biological models is useful for monitoring the environment. In this study, potential cytotoxic and genotoxic damages in Plagioscion squamosissimus (commonl...

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Bibliographic Details
Published in:Ecotoxicology and environmental safety 2016-10, Vol.132, p.111-115
Main Authors: Rocha, Carlos Alberto Machado da, Pessoa, Carla Mariana Ferreira, Rodrigues, Claudia Antonia Campos, Pinheiro, Raul Henrique da Silva, Costa, Edmar Tavares da, Guimarães, Adriana Costa, Burbano, Rommel Rodríguez
Format: Article
Language:English
Subjects:
Animals
Apoptosis - drug effects
Brazil
Cell Cycle - drug effects
Cytotoxins - toxicity
DNA Damage
Environmental Monitoring
Erythrocytes - drug effects
Fish erythrocytes
Flow cytometry
Freshwater
Marajó archipelago
Micronucleus test
Micronucleus Tests
Mutagens - toxicity
Perciformes
Perciformes - genetics
Plagioscion squamosissimus
Rivers
Sciaenidae
Water Pollutants - toxicity
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Summary:Maintaining water quality within tolerable limits is a basic need of the riverside communities in the Amazon. Using endemic aquatic organisms as biological models is useful for monitoring the environment. In this study, potential cytotoxic and genotoxic damages in Plagioscion squamosissimus (commonly known as silver croaker) from the Marajó Archipelago were evaluated using a flow cytometry assay and a survey of micronuclei (MN) frequency as well as other nuclear abnormalities (NA). P. squamosissimus specimens were collected at four locations in the Marajó Archipelago. Blood samples from these fish were used in the flow cytometry assay and piscine micronucleus test, and the resulting data were analyzed using analysis of variance (ANOVA). We did not observe a difference in the erythrocyte cell cycle distribution among the samples (P=0.9992), which suggests the absence of cytotoxic agent-induced apoptosis. The piscine micronucleus test exhibited differences in the samples from São Sebastião da Boa Vista (SSBV), and those from Anajás produced the highest mutagenicity indices. The MN frequencies were low for all groups, but the groups exhibited significantly different frequencies (P=0.0033). Reniform nuclei, nuclei with extensions, and lobed nuclei were combined and considered NA. The frequency differences for these NA were significant among sampling sites (P
ISSN:0147-6513
1090-2414
DOI:10.1016/j.ecoenv.2016.05.020