Associations between polycyclic aromatic hydrocarbon (PAH) exposure and oxidative stress in people living near e-waste recycling facilities in China

Emission of polycyclic aromatic hydrocarbons (PAHs) from e-waste recycling activities in China is known. However, little is known on the association between PAH exposure and oxidative damage to DNA and lipid content in people living near e-waste dismantling sites. In this study, ten hydroxylated pol...

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Bibliographic Details
Published in:Environment international 2016-09, Vol.94, p.161-169
Main Authors: Lu, Shao-you, Li, Yan-xi, Zhang, Jian-qing, Zhang, Tao, Liu, Gui-hua, Huang, Ming-zhi, Li, Xiao, Ruan, Ju-jun, Kannan, Kurunthachalam, Qiu, Rong-liang
Format: Article
Language:English
Subjects:
8-hydroxy-2′-deoxyguanosine
Adult
Biomarkers - urine
China
Deoxyguanosine - analogs & derivatives
Deoxyguanosine - urine
E-waste recycling
Electronic Waste
Environmental Exposure - adverse effects
Environmental Pollutants - urine
Female
Humans
Male
Malondialdehyde
Malondialdehyde - urine
Middle Aged
Oxidative Stress
Polycyclic aromatic hydrocarbons
Polycyclic Aromatic Hydrocarbons - urine
Recycling
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Summary:Emission of polycyclic aromatic hydrocarbons (PAHs) from e-waste recycling activities in China is known. However, little is known on the association between PAH exposure and oxidative damage to DNA and lipid content in people living near e-waste dismantling sites. In this study, ten hydroxylated polycyclic aromatic hydrocarbons (OH-PAHs) and two biomarkers [8-hydroxy-2′-deoxyguanosine (8-OHdG) and malondialdehyde (MDA)] of oxidative stress were investigated in urine samples collected from people living in and around e-waste dismantling facilities, and in reference population from rural and urban areas in China. The urinary levels of ∑10OH-PAHs determined in e-waste recycling area (GM: 25.4μg/g Cre) were significantly higher (p
ISSN:0160-4120
1873-6750
DOI:10.1016/j.envint.2016.05.021