Loading…

Periprocedural 3D imaging of the left atrium and esophagus: comparison of different protocols of 3D rotational angiography of the left atrium and esophagus in group of 547 consecutive patients undergoing catheter ablation of the complex atrial arrhythmias

A new method in creating 3D models of the left atrium (LA) and esophagus before catheter ablation of atrial arrhythmias is 3D rotational angiography (3DRA) of the LA. The purpose of this retrospective study was to test various acquisition protocols of the 3DRA and attempt to define the parameters in...

Full description

Saved in:
Bibliographic Details
Published in:International Journal of Cardiovascular Imaging 2016-07, Vol.32 (7), p.1011-1019
Main Authors: Starek, Zdenek, Lehar, František, Jez, Jiri, Wolf, Jiri, Kulik, Tomas, Zbankova, Alena, Novak, Miroslav
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c405t-ad6d034a837b1639d241d3535c3ddac723505f90ad5f27d1f234b26445e0ccd03
cites cdi_FETCH-LOGICAL-c405t-ad6d034a837b1639d241d3535c3ddac723505f90ad5f27d1f234b26445e0ccd03
container_end_page 1019
container_issue 7
container_start_page 1011
container_title International Journal of Cardiovascular Imaging
container_volume 32
creator Starek, Zdenek
Lehar, František
Jez, Jiri
Wolf, Jiri
Kulik, Tomas
Zbankova, Alena
Novak, Miroslav
description A new method in creating 3D models of the left atrium (LA) and esophagus before catheter ablation of atrial arrhythmias is 3D rotational angiography (3DRA) of the LA. The purpose of this retrospective study was to test various acquisition protocols of the 3DRA and attempt to define the parameters influencing the success of the protocols. From August 2010 to November 2014, 3DRA of the LA using the Philips Allura FD 10 X-ray system was performed in 547 consecutive patients using right atrial and left atrial protocols. Visualization of the esophagus was performed after oral administration of a contrast agent. Patients were monitored for success (creation of a useful 3D models) and evaluated for a number of parameters affecting the success of 3DRA. The success of the RA protocol was 88.89 % with and 91.91 % without esophagus imaging. The success of the LA protocol was 97.42 % with and 94.54 % without esophagus imaging. The only factor reducing the success of the RA protocol was BMI; the LA protocol was not influenced by any factor. Ventricular fibrillation induced in two patients was successfully treated with defibrillation. 3DRA of the LA is a reliable method that supports catheter ablation of complex atrial arrhythmias. The LA protocol with esophagus imaging was significantly more reliable than the RA protocol; the other protocols were comparable. The RA protocol may be negatively affected by high BMI. Simultaneous imaging of the esophagus is safe and feasible, and the LA protocol can be recommended.
doi_str_mv 10.1007/s10554-016-0888-y
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1811901060</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>4149461181</sourcerecordid><originalsourceid>FETCH-LOGICAL-c405t-ad6d034a837b1639d241d3535c3ddac723505f90ad5f27d1f234b26445e0ccd03</originalsourceid><addsrcrecordid>eNqNkkuL1jAUhosozjj6A9xIwI2b6smt6edOxisM6ELXJV-SthnapOYi9tdrOp1PRBBd9fac5z2kb1U9xvAcA4gXEQPnrAbc1NC2bb3eqc4xF7QGwejd7b451Fwc2Fn1IMZrACBA6P3qjAiMG0LFefXjkwl2CV4ZnYOcEH2N7CwH6wbke5RGgybTJyRTsHlG0mlkol9GOeT4Eik_LzLY6N0Ga9v3JhiXUPElr_wUt9fFWB5lst4Vv3SD9UOQy7j-MwBZh4bg87KRnImS56JROdlvBi3FWLIiyk6bMPhtYyWLL5mA5HG6CTxFbItO5vtNyrZECOOaxtnK-LC618spmke314vqy9s3ny_f11cf3324fHVVKwY81VI3GiiTLRVH3NCDJgxryilXVGupBKEceH8AqXlPhMY9oexIGsa4AaXK6EX1bPeWs_maTUzdbKMy0ySd8Tl2uMX4ABia_0FBQFvQtqBP_0CvfQ7lnE9CsgvxTqngYwym75ZQfnJYOwzdVqRuL1JXitRtRerWMvPk1pyPs9G_Jk7NKQDZgVg-ucGE36L_av0J-ivZPQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1811902060</pqid></control><display><type>article</type><title>Periprocedural 3D imaging of the left atrium and esophagus: comparison of different protocols of 3D rotational angiography of the left atrium and esophagus in group of 547 consecutive patients undergoing catheter ablation of the complex atrial arrhythmias</title><source>Springer Nature</source><creator>Starek, Zdenek ; Lehar, František ; Jez, Jiri ; Wolf, Jiri ; Kulik, Tomas ; Zbankova, Alena ; Novak, Miroslav</creator><creatorcontrib>Starek, Zdenek ; Lehar, František ; Jez, Jiri ; Wolf, Jiri ; Kulik, Tomas ; Zbankova, Alena ; Novak, Miroslav</creatorcontrib><description>A new method in creating 3D models of the left atrium (LA) and esophagus before catheter ablation of atrial arrhythmias is 3D rotational angiography (3DRA) of the LA. The purpose of this retrospective study was to test various acquisition protocols of the 3DRA and attempt to define the parameters influencing the success of the protocols. From August 2010 to November 2014, 3DRA of the LA using the Philips Allura FD 10 X-ray system was performed in 547 consecutive patients using right atrial and left atrial protocols. Visualization of the esophagus was performed after oral administration of a contrast agent. Patients were monitored for success (creation of a useful 3D models) and evaluated for a number of parameters affecting the success of 3DRA. The success of the RA protocol was 88.89 % with and 91.91 % without esophagus imaging. The success of the LA protocol was 97.42 % with and 94.54 % without esophagus imaging. The only factor reducing the success of the RA protocol was BMI; the LA protocol was not influenced by any factor. Ventricular fibrillation induced in two patients was successfully treated with defibrillation. 3DRA of the LA is a reliable method that supports catheter ablation of complex atrial arrhythmias. The LA protocol with esophagus imaging was significantly more reliable than the RA protocol; the other protocols were comparable. The RA protocol may be negatively affected by high BMI. Simultaneous imaging of the esophagus is safe and feasible, and the LA protocol can be recommended.</description><identifier>ISSN: 1569-5794</identifier><identifier>EISSN: 1573-0743</identifier><identifier>EISSN: 1875-8312</identifier><identifier>DOI: 10.1007/s10554-016-0888-y</identifier><identifier>PMID: 27116237</identifier><identifier>CODEN: IJCIBI</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Aged ; Angiography - methods ; Atrial Fibrillation - diagnostic imaging ; Atrial Fibrillation - physiopathology ; Atrial Fibrillation - surgery ; Body Mass Index ; Cardiac Imaging ; Cardiology ; Catheter Ablation ; Computer Simulation ; Contrast Media - administration &amp; dosage ; Esophagus - diagnostic imaging ; Female ; Heart Atria - diagnostic imaging ; Heart Atria - physiopathology ; Heart Atria - surgery ; Humans ; Imaging ; Imaging, Three-Dimensional ; Iohexol - administration &amp; dosage ; Iohexol - analogs &amp; derivatives ; Male ; Medicine ; Medicine &amp; Public Health ; Middle Aged ; Models, Cardiovascular ; Original Paper ; Predictive Value of Tests ; Radiographic Image Interpretation, Computer-Assisted ; Radiology ; Reproducibility of Results ; Retrospective Studies</subject><ispartof>International Journal of Cardiovascular Imaging, 2016-07, Vol.32 (7), p.1011-1019</ispartof><rights>Springer Science+Business Media Dordrecht 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c405t-ad6d034a837b1639d241d3535c3ddac723505f90ad5f27d1f234b26445e0ccd03</citedby><cites>FETCH-LOGICAL-c405t-ad6d034a837b1639d241d3535c3ddac723505f90ad5f27d1f234b26445e0ccd03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27116237$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Starek, Zdenek</creatorcontrib><creatorcontrib>Lehar, František</creatorcontrib><creatorcontrib>Jez, Jiri</creatorcontrib><creatorcontrib>Wolf, Jiri</creatorcontrib><creatorcontrib>Kulik, Tomas</creatorcontrib><creatorcontrib>Zbankova, Alena</creatorcontrib><creatorcontrib>Novak, Miroslav</creatorcontrib><title>Periprocedural 3D imaging of the left atrium and esophagus: comparison of different protocols of 3D rotational angiography of the left atrium and esophagus in group of 547 consecutive patients undergoing catheter ablation of the complex atrial arrhythmias</title><title>International Journal of Cardiovascular Imaging</title><addtitle>Int J Cardiovasc Imaging</addtitle><addtitle>Int J Cardiovasc Imaging</addtitle><description>A new method in creating 3D models of the left atrium (LA) and esophagus before catheter ablation of atrial arrhythmias is 3D rotational angiography (3DRA) of the LA. The purpose of this retrospective study was to test various acquisition protocols of the 3DRA and attempt to define the parameters influencing the success of the protocols. From August 2010 to November 2014, 3DRA of the LA using the Philips Allura FD 10 X-ray system was performed in 547 consecutive patients using right atrial and left atrial protocols. Visualization of the esophagus was performed after oral administration of a contrast agent. Patients were monitored for success (creation of a useful 3D models) and evaluated for a number of parameters affecting the success of 3DRA. The success of the RA protocol was 88.89 % with and 91.91 % without esophagus imaging. The success of the LA protocol was 97.42 % with and 94.54 % without esophagus imaging. The only factor reducing the success of the RA protocol was BMI; the LA protocol was not influenced by any factor. Ventricular fibrillation induced in two patients was successfully treated with defibrillation. 3DRA of the LA is a reliable method that supports catheter ablation of complex atrial arrhythmias. The LA protocol with esophagus imaging was significantly more reliable than the RA protocol; the other protocols were comparable. The RA protocol may be negatively affected by high BMI. Simultaneous imaging of the esophagus is safe and feasible, and the LA protocol can be recommended.</description><subject>Aged</subject><subject>Angiography - methods</subject><subject>Atrial Fibrillation - diagnostic imaging</subject><subject>Atrial Fibrillation - physiopathology</subject><subject>Atrial Fibrillation - surgery</subject><subject>Body Mass Index</subject><subject>Cardiac Imaging</subject><subject>Cardiology</subject><subject>Catheter Ablation</subject><subject>Computer Simulation</subject><subject>Contrast Media - administration &amp; dosage</subject><subject>Esophagus - diagnostic imaging</subject><subject>Female</subject><subject>Heart Atria - diagnostic imaging</subject><subject>Heart Atria - physiopathology</subject><subject>Heart Atria - surgery</subject><subject>Humans</subject><subject>Imaging</subject><subject>Imaging, Three-Dimensional</subject><subject>Iohexol - administration &amp; dosage</subject><subject>Iohexol - analogs &amp; derivatives</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Middle Aged</subject><subject>Models, Cardiovascular</subject><subject>Original Paper</subject><subject>Predictive Value of Tests</subject><subject>Radiographic Image Interpretation, Computer-Assisted</subject><subject>Radiology</subject><subject>Reproducibility of Results</subject><subject>Retrospective Studies</subject><issn>1569-5794</issn><issn>1573-0743</issn><issn>1875-8312</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNqNkkuL1jAUhosozjj6A9xIwI2b6smt6edOxisM6ELXJV-SthnapOYi9tdrOp1PRBBd9fac5z2kb1U9xvAcA4gXEQPnrAbc1NC2bb3eqc4xF7QGwejd7b451Fwc2Fn1IMZrACBA6P3qjAiMG0LFefXjkwl2CV4ZnYOcEH2N7CwH6wbke5RGgybTJyRTsHlG0mlkol9GOeT4Eik_LzLY6N0Ga9v3JhiXUPElr_wUt9fFWB5lst4Vv3SD9UOQy7j-MwBZh4bg87KRnImS56JROdlvBi3FWLIiyk6bMPhtYyWLL5mA5HG6CTxFbItO5vtNyrZECOOaxtnK-LC618spmke314vqy9s3ny_f11cf3324fHVVKwY81VI3GiiTLRVH3NCDJgxryilXVGupBKEceH8AqXlPhMY9oexIGsa4AaXK6EX1bPeWs_maTUzdbKMy0ySd8Tl2uMX4ABia_0FBQFvQtqBP_0CvfQ7lnE9CsgvxTqngYwym75ZQfnJYOwzdVqRuL1JXitRtRerWMvPk1pyPs9G_Jk7NKQDZgVg-ucGE36L_av0J-ivZPQ</recordid><startdate>20160701</startdate><enddate>20160701</enddate><creator>Starek, Zdenek</creator><creator>Lehar, František</creator><creator>Jez, Jiri</creator><creator>Wolf, Jiri</creator><creator>Kulik, Tomas</creator><creator>Zbankova, Alena</creator><creator>Novak, Miroslav</creator><general>Springer Netherlands</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M7Z</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>7QO</scope></search><sort><creationdate>20160701</creationdate><title>Periprocedural 3D imaging of the left atrium and esophagus: comparison of different protocols of 3D rotational angiography of the left atrium and esophagus in group of 547 consecutive patients undergoing catheter ablation of the complex atrial arrhythmias</title><author>Starek, Zdenek ; Lehar, František ; Jez, Jiri ; Wolf, Jiri ; Kulik, Tomas ; Zbankova, Alena ; Novak, Miroslav</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c405t-ad6d034a837b1639d241d3535c3ddac723505f90ad5f27d1f234b26445e0ccd03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Aged</topic><topic>Angiography - methods</topic><topic>Atrial Fibrillation - diagnostic imaging</topic><topic>Atrial Fibrillation - physiopathology</topic><topic>Atrial Fibrillation - surgery</topic><topic>Body Mass Index</topic><topic>Cardiac Imaging</topic><topic>Cardiology</topic><topic>Catheter Ablation</topic><topic>Computer Simulation</topic><topic>Contrast Media - administration &amp; dosage</topic><topic>Esophagus - diagnostic imaging</topic><topic>Female</topic><topic>Heart Atria - diagnostic imaging</topic><topic>Heart Atria - physiopathology</topic><topic>Heart Atria - surgery</topic><topic>Humans</topic><topic>Imaging</topic><topic>Imaging, Three-Dimensional</topic><topic>Iohexol - administration &amp; dosage</topic><topic>Iohexol - analogs &amp; derivatives</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Middle Aged</topic><topic>Models, Cardiovascular</topic><topic>Original Paper</topic><topic>Predictive Value of Tests</topic><topic>Radiographic Image Interpretation, Computer-Assisted</topic><topic>Radiology</topic><topic>Reproducibility of Results</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Starek, Zdenek</creatorcontrib><creatorcontrib>Lehar, František</creatorcontrib><creatorcontrib>Jez, Jiri</creatorcontrib><creatorcontrib>Wolf, Jiri</creatorcontrib><creatorcontrib>Kulik, Tomas</creatorcontrib><creatorcontrib>Zbankova, Alena</creatorcontrib><creatorcontrib>Novak, Miroslav</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest_Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><jtitle>International Journal of Cardiovascular Imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Starek, Zdenek</au><au>Lehar, František</au><au>Jez, Jiri</au><au>Wolf, Jiri</au><au>Kulik, Tomas</au><au>Zbankova, Alena</au><au>Novak, Miroslav</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Periprocedural 3D imaging of the left atrium and esophagus: comparison of different protocols of 3D rotational angiography of the left atrium and esophagus in group of 547 consecutive patients undergoing catheter ablation of the complex atrial arrhythmias</atitle><jtitle>International Journal of Cardiovascular Imaging</jtitle><stitle>Int J Cardiovasc Imaging</stitle><addtitle>Int J Cardiovasc Imaging</addtitle><date>2016-07-01</date><risdate>2016</risdate><volume>32</volume><issue>7</issue><spage>1011</spage><epage>1019</epage><pages>1011-1019</pages><issn>1569-5794</issn><eissn>1573-0743</eissn><eissn>1875-8312</eissn><coden>IJCIBI</coden><abstract>A new method in creating 3D models of the left atrium (LA) and esophagus before catheter ablation of atrial arrhythmias is 3D rotational angiography (3DRA) of the LA. The purpose of this retrospective study was to test various acquisition protocols of the 3DRA and attempt to define the parameters influencing the success of the protocols. From August 2010 to November 2014, 3DRA of the LA using the Philips Allura FD 10 X-ray system was performed in 547 consecutive patients using right atrial and left atrial protocols. Visualization of the esophagus was performed after oral administration of a contrast agent. Patients were monitored for success (creation of a useful 3D models) and evaluated for a number of parameters affecting the success of 3DRA. The success of the RA protocol was 88.89 % with and 91.91 % without esophagus imaging. The success of the LA protocol was 97.42 % with and 94.54 % without esophagus imaging. The only factor reducing the success of the RA protocol was BMI; the LA protocol was not influenced by any factor. Ventricular fibrillation induced in two patients was successfully treated with defibrillation. 3DRA of the LA is a reliable method that supports catheter ablation of complex atrial arrhythmias. The LA protocol with esophagus imaging was significantly more reliable than the RA protocol; the other protocols were comparable. The RA protocol may be negatively affected by high BMI. Simultaneous imaging of the esophagus is safe and feasible, and the LA protocol can be recommended.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><pmid>27116237</pmid><doi>10.1007/s10554-016-0888-y</doi><tpages>9</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1569-5794
ispartof International Journal of Cardiovascular Imaging, 2016-07, Vol.32 (7), p.1011-1019
issn 1569-5794
1573-0743
1875-8312
language eng
recordid cdi_proquest_miscellaneous_1811901060
source Springer Nature
subjects Aged
Angiography - methods
Atrial Fibrillation - diagnostic imaging
Atrial Fibrillation - physiopathology
Atrial Fibrillation - surgery
Body Mass Index
Cardiac Imaging
Cardiology
Catheter Ablation
Computer Simulation
Contrast Media - administration & dosage
Esophagus - diagnostic imaging
Female
Heart Atria - diagnostic imaging
Heart Atria - physiopathology
Heart Atria - surgery
Humans
Imaging
Imaging, Three-Dimensional
Iohexol - administration & dosage
Iohexol - analogs & derivatives
Male
Medicine
Medicine & Public Health
Middle Aged
Models, Cardiovascular
Original Paper
Predictive Value of Tests
Radiographic Image Interpretation, Computer-Assisted
Radiology
Reproducibility of Results
Retrospective Studies
title Periprocedural 3D imaging of the left atrium and esophagus: comparison of different protocols of 3D rotational angiography of the left atrium and esophagus in group of 547 consecutive patients undergoing catheter ablation of the complex atrial arrhythmias
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T07%3A08%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Periprocedural%203D%20imaging%20of%20the%20left%20atrium%20and%20esophagus:%20comparison%20of%20different%20protocols%20of%203D%20rotational%20angiography%20of%20the%20left%20atrium%20and%20esophagus%20in%20group%20of%20547%20consecutive%20patients%20undergoing%20catheter%20ablation%20of%20the%20complex%20atrial%20arrhythmias&rft.jtitle=International%20Journal%20of%20Cardiovascular%20Imaging&rft.au=Starek,%20Zdenek&rft.date=2016-07-01&rft.volume=32&rft.issue=7&rft.spage=1011&rft.epage=1019&rft.pages=1011-1019&rft.issn=1569-5794&rft.eissn=1573-0743&rft.coden=IJCIBI&rft_id=info:doi/10.1007/s10554-016-0888-y&rft_dat=%3Cproquest_cross%3E4149461181%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c405t-ad6d034a837b1639d241d3535c3ddac723505f90ad5f27d1f234b26445e0ccd03%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1811902060&rft_id=info:pmid/27116237&rfr_iscdi=true