Positive Lymph Node Ratio as an Indicator of Prognosis and Local Tumor Clearance in N3 Gastric Cancer

Background Nodal metastasis is an important clinical issue in gastric cancer patients. This study was designed to investigate the clinical usefulness of the positive lymph node ratio (PLNR), which reflects both metastatic and retrieved lymph node numbers, in patients with pN3 gastric cancer. Methods...

Full description

Saved in:
Bibliographic Details
Published in:Journal of gastrointestinal surgery 2016-09, Vol.20 (9), p.1565-1571
Main Authors: Komatsu, Shuhei, Ichikawa, Daisuke, Miyamae, Mahito, Kosuga, Toshiyuki, Okamoto, Kazuma, Arita, Tomohiro, Konishi, Hirotaka, Morimura, Ryo, Murayama, Yasutoshi, Shiozaki, Atsushi, Kuriu, Yoshiaki, Ikoma, Hisashi, Nakanishi, Masayoshi, Fujiwara, Hitoshi, Otsuji, Eigo
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Aged, 80 and over
Antigens
Cancer therapies
Chemotherapy
Female
Gastrectomy
Gastric cancer
Gastroenterology
Gastrointestinal surgery
Humans
Lymph Node Excision
Lymph Nodes - pathology
Lymph Nodes - surgery
Lymphatic Metastasis
Lymphatic system
Male
Medical prognosis
Medicine
Medicine & Public Health
Metastasis
Middle Aged
Neoplasm Recurrence, Local - pathology
Neoplasm Staging
Original Article
Prognosis
Retrospective Studies
Stomach Neoplasms - pathology
Stomach Neoplasms - surgery
Surgery
Tomography
Tumor Burden
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Nodal metastasis is an important clinical issue in gastric cancer patients. This study was designed to investigate the clinical usefulness of the positive lymph node ratio (PLNR), which reflects both metastatic and retrieved lymph node numbers, in patients with pN3 gastric cancer. Methods We retrospectively analyzed the records of 138 consecutive pN3 patients who underwent curative gastrectomy with lymphadenectomy from 2000 to 2012. Results A PLNR of 0.4 was proved to be the best cutoff value to stratify the prognosis of patients with pN3 gastric cancer ( P  
ISSN:1091-255X
1873-4626
DOI:10.1007/s11605-016-3197-9