Twelve-month and sixty-month outcomes of noncultured cellular grafting for vitiligo

Background Noncultured cellular grafting is a known surgical technique for vitiligo. Objective This study evaluated our center's 12-month repigmentation outcome and its maintenance up to 60 months, factors influencing repigmentation and safety data. Methods Clinicoepidemiologic and repigmentati...

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Published in:Journal of the American Academy of Dermatology 2016-09, Vol.75 (3), p.564-571
Main Authors: Gan, Emily Yiping, MBBS(Honors), MRCP(UK), MMed(Int Med), Kong, Yan Ling, MBBS, Tan, Wei Ding, MSc (Statistics), Thng, Steven T., MBBS, MRCP (UK), FRCP (Edin), Goh, Boon Kee, BSc(Hons), MBChB(UK), MRCP(UK), FRCP(Edin)
Format: Article
Language:English
Subjects:
Adult
Databases, Factual
Dermatology
Epidermis - cytology
Epidermis - transplantation
Esthetics
Female
Follow-Up Studies
Graft Rejection
Graft Survival
Humans
Male
Middle Aged
noncultured cellular grafting
repigmentation
Retrospective Studies
Risk Assessment
Severity of Illness Index
Singapore
Skin Pigmentation - physiology
Skin Transplantation - adverse effects
Skin Transplantation - methods
Tertiary Care Centers
Time Factors
Treatment Outcome
Vitiligo - diagnosis
Vitiligo - surgery
Wound Healing - physiology
Young Adult
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Summary:Background Noncultured cellular grafting is a known surgical technique for vitiligo. Objective This study evaluated our center's 12-month repigmentation outcome and its maintenance up to 60 months, factors influencing repigmentation and safety data. Methods Clinicoepidemiologic and repigmentation data were reviewed for patients with vitiligo who had undergone noncultured cellular grafting from March 2006 to December 2012 at the National Skin Center, Singapore. Results All 177 patients who received noncultured cellular grafting during the study period were included. For those with available data, good to excellent repigmentation was present in 83% at 60 months. At 12 months, 88% of patients (n = 52) with segmental vitiligo achieved good to excellent repigmentation compared with 71% (n = 55) with nonsegmental vitiligo ( P  
ISSN:0190-9622
1097-6787
DOI:10.1016/j.jaad.2016.04.007