H1N1 influenza presenting as severe acute pancreatitis and multiorgan dysfunction

Throat swab reverse transcriptase polymerase chain reaction was positive for H1N1 influenza virus; chest radiograph showed no homogenous parenchymal opacities in bilateral mid and lower zones with relative sparing of apices (Fig. 1). In vitro studies in animal models have confirmed that H1N1 viruses...

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Bibliographic Details
Published in:The American journal of emergency medicine 2016-09, Vol.34 (9), p.1911.e1-1911.e2
Main Authors: Habib, Anwer, MD, Jain, Abhinav, MD, Singh, Bhawani, DM, Jamshed, Nayer, MD
Format: Article
Language:English
Subjects:
Abdomen
Acute Kidney Injury - blood
Acute Kidney Injury - diagnosis
Acute Kidney Injury - etiology
Acute Kidney Injury - virology
Adult
Alcohol
Amylases - blood
Animal models
Ascites - diagnostic imaging
Ascites - etiology
Blood Urea Nitrogen
Creatinine - blood
Emergency
Emergency medical care
Female
Glucose
Guillain-Barre syndrome
Hepatomegaly - diagnostic imaging
Hepatomegaly - etiology
Humans
Infections
Influenza A Virus, H1N1 Subtype - genetics
Influenza, Human - complications
Influenza, Human - diagnosis
Intensive care
Lipase - blood
Medical imaging
Multiple Organ Failure - diagnostic imaging
Multiple Organ Failure - etiology
Multiple Organ Failure - virology
Pain
Pancreas
Pancreatitis - blood
Pancreatitis - diagnostic imaging
Pancreatitis - etiology
Pancreatitis - virology
Pneumonia
Potassium
Radiography, Thoracic
Respiratory distress syndrome
Respiratory Distress Syndrome, Adult - diagnostic imaging
Respiratory Distress Syndrome, Adult - etiology
Respiratory Distress Syndrome, Adult - virology
Reverse Transcriptase Polymerase Chain Reaction
Splenomegaly - diagnostic imaging
Splenomegaly - etiology
Swine flu
Tomography, X-Ray Computed
Tuberculosis
Ultrasonography
Viruses
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Description
Summary:Throat swab reverse transcriptase polymerase chain reaction was positive for H1N1 influenza virus; chest radiograph showed no homogenous parenchymal opacities in bilateral mid and lower zones with relative sparing of apices (Fig. 1). In vitro studies in animal models have confirmed that H1N1 viruses can grow and produce cell damage in human pancreatic islets and other pancreatic cell lines, causing AP and diabetes [5].
ISSN:0735-6757
1532-8171
DOI:10.1016/j.ajem.2016.01.019