Modular Attachment of Appended Boron Lewis Acids to a Ruthenium Pincer Catalyst: Metal–Ligand Cooperativity Enables Selective Alkyne Hydrogenation

A new series of bifunctional Ru complexes with pendent Lewis acidic boranes were prepared by late-stage modification of an active hydrogen-transfer catalyst. The appended boranes modulate the reactivity of a metal hydride as well as catalytic hydrogenations. After installing acidic auxiliary groups,...

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Bibliographic Details
Published in:Journal of the American Chemical Society 2016-08, Vol.138 (33), p.10378-10381
Main Authors: Tseng, Kuei-Nin T, Kampf, Jeff W, Szymczak, Nathaniel K
Format: Article
Language:English
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Summary:A new series of bifunctional Ru complexes with pendent Lewis acidic boranes were prepared by late-stage modification of an active hydrogen-transfer catalyst. The appended boranes modulate the reactivity of a metal hydride as well as catalytic hydrogenations. After installing acidic auxiliary groups, the complexes become multifunctional and catalyze the cis-selective hydrogenation of alkynes with higher rates, conversions, and selectivities compared with the unmodified catalyst.
ISSN:0002-7863
1520-5126
DOI:10.1021/jacs.6b03972