Strategies for bioengineered scaffolds that support adipose stem cells in regenerative therapies

Regenerative medicine possesses the potential to ameliorate damage to tissue that results from a vast range of conditions, including traumatic injury, tumor resection and inherited tissue defects. Adult stem cells, while more limited in their potential than pluripotent stem cells, are still capable...

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Bibliographic Details
Published in:Regenerative medicine 2016-09, Vol.11 (6), p.589-599
Main Authors: Clevenger, Tracy N, Luna, Gabriel, Fisher, Steven K, Clegg, Dennis O
Format: Article
Language:English
Subjects:
3D scaffolds
Adipose Tissue - cytology
Adipose Tissue - transplantation
adipose-derived stem cells
Animals
ASC
cartilaginous regeneration
Cell- and Tissue-Based Therapy
Humans
osteogenic regeneration
Regeneration - physiology
regenerative medicine
soft-tissue regeneration
Stem Cell Transplantation
Stem Cells - cytology
synthetic scaffold
Tissue Engineering - methods
Tissue Scaffolds
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Summary:Regenerative medicine possesses the potential to ameliorate damage to tissue that results from a vast range of conditions, including traumatic injury, tumor resection and inherited tissue defects. Adult stem cells, while more limited in their potential than pluripotent stem cells, are still capable of differentiating into numerous lineages and provide feasible allogeneic and autologous treatment options for many conditions. Adipose stem cells are one of the most abundant types of stem cell in the adult human. Here, we review recent advances in the development of synthetic scaffolding systems used in concert with adipose stem cells and assess their potential use for clinical applications.
ISSN:1746-0751
1746-076X
DOI:10.2217/rme-2016-0064