The Role of Positron Emission Tomography With (68)Gallium (Ga)-Labeled Prostate-specific Membrane Antigen (PSMA) in the Management of Patients With Organ-confined and Locally Advanced Prostate Cancer Prior to Radical Treatment and After Radical Prostatectomy

The role of positron emission tomography (PET) with (68)Gallium (Ga)-labeled prostate-specific membrane antigen (PSMA) imaging for prostate cancer is gaining prominence. Current imaging strategies, despite having progressed significantly, have limitations, in particular their ability to diagnose met...

Full description

Saved in:
Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2016-09, Vol.95, p.11-15
Main Authors: Rai, Bhavan Prasad, Baum, Richard Paul, Patel, Amit, Hughes, Robert, Alonzi, Roberto, Lane, Tim, Adshead, Jim, Vasdev, Nikhil
Format: Article
Language:English
Subjects:
Antigens, Surface
Gallium Radioisotopes
Glutamate Carboxypeptidase II
Humans
Male
Neoplasm Recurrence, Local - diagnostic imaging
Positron-Emission Tomography - methods
Preoperative Care
Prostatectomy
Prostatic Neoplasms - diagnostic imaging
Prostatic Neoplasms - pathology
Prostatic Neoplasms - surgery
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites
container_end_page 15
container_issue
container_start_page 11
container_title Urology (Ridgewood, N.J.)
container_volume 95
creator Rai, Bhavan Prasad
Baum, Richard Paul
Patel, Amit
Hughes, Robert
Alonzi, Roberto
Lane, Tim
Adshead, Jim
Vasdev, Nikhil
description The role of positron emission tomography (PET) with (68)Gallium (Ga)-labeled prostate-specific membrane antigen (PSMA) imaging for prostate cancer is gaining prominence. Current imaging strategies, despite having progressed significantly, have limitations, in particular their ability to diagnose metastatic lymph node involvement. Preliminary results of PET with (68)Ga-labeled PSMA have shown encouraging results, particularly in the recurrent prostate cancer setting. Furthermore, the ability of PET with (68)Ga-labeled PSMA of playing a dual diagnostic and therapeutic setting (theranostics) is currently being investigated as well. PET with (68)Ga-labeled PSMA certainly has a role to play in bridging some of the voids in contemporary prostate cancer imaging tools.
doi_str_mv 10.1016/j.urology.2015.12.048
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1814658047</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1814658047</sourcerecordid><originalsourceid>FETCH-LOGICAL-p211t-1dcac3d3b82ebb16421b9852944e96f920525328249b05bea82c9dca9539d8a83</originalsourceid><addsrcrecordid>eNpNkU9r3DAQxd1ASdI0H6FljrsHu5JseaWjWdJtYZcs6YYcF1mWvQq25EpywN--yp-FnmaGee_9YCZJvmGUYYTLH8_Z5GxvuzkjCNMMkwwV7CK5xpSsUs45vUq-eP-MECrLcnWZXJFyxRFl7PrTxeGk4MH2CmwLe-t1cNbA3aC917E52MF2ToynGZ50OMGiZMuN6Hs9DbDYiGW6FbXqVQN7Z30QQaV-VFK3WsJODbUTRkFlgu6UgcX-z65agjYQInMnjOjUoEx4I4ugY-vfKfeuEyaV1rTaxGxhGthaGbEzVM2LMPI_IKxfZxdnbR0ECw-i0VELB6dEeMt_9VdtiKLz7myWwQ7z1-RzK3qvbj_qTfL48-6w_pVu7ze_19U2HQnGIcWNFDJv8poRVde4LAiuOaOEF4XiZcsJooTmhJGC14jWSjAiefRwmvOGCZbfJIv33NHZv5Py4RivLFXfxyPZyR8xw0VJGSpWUfr9QzrVg2qOo9ODcPPx_Lf8H06HnSc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1814658047</pqid></control><display><type>article</type><title>The Role of Positron Emission Tomography With (68)Gallium (Ga)-Labeled Prostate-specific Membrane Antigen (PSMA) in the Management of Patients With Organ-confined and Locally Advanced Prostate Cancer Prior to Radical Treatment and After Radical Prostatectomy</title><source>ScienceDirect Journals</source><creator>Rai, Bhavan Prasad ; Baum, Richard Paul ; Patel, Amit ; Hughes, Robert ; Alonzi, Roberto ; Lane, Tim ; Adshead, Jim ; Vasdev, Nikhil</creator><creatorcontrib>Rai, Bhavan Prasad ; Baum, Richard Paul ; Patel, Amit ; Hughes, Robert ; Alonzi, Roberto ; Lane, Tim ; Adshead, Jim ; Vasdev, Nikhil</creatorcontrib><description>The role of positron emission tomography (PET) with (68)Gallium (Ga)-labeled prostate-specific membrane antigen (PSMA) imaging for prostate cancer is gaining prominence. Current imaging strategies, despite having progressed significantly, have limitations, in particular their ability to diagnose metastatic lymph node involvement. Preliminary results of PET with (68)Ga-labeled PSMA have shown encouraging results, particularly in the recurrent prostate cancer setting. Furthermore, the ability of PET with (68)Ga-labeled PSMA of playing a dual diagnostic and therapeutic setting (theranostics) is currently being investigated as well. PET with (68)Ga-labeled PSMA certainly has a role to play in bridging some of the voids in contemporary prostate cancer imaging tools.</description><identifier>EISSN: 1527-9995</identifier><identifier>DOI: 10.1016/j.urology.2015.12.048</identifier><identifier>PMID: 26790588</identifier><language>eng</language><publisher>United States</publisher><subject>Antigens, Surface ; Gallium Radioisotopes ; Glutamate Carboxypeptidase II ; Humans ; Male ; Neoplasm Recurrence, Local - diagnostic imaging ; Positron-Emission Tomography - methods ; Preoperative Care ; Prostatectomy ; Prostatic Neoplasms - diagnostic imaging ; Prostatic Neoplasms - pathology ; Prostatic Neoplasms - surgery</subject><ispartof>Urology (Ridgewood, N.J.), 2016-09, Vol.95, p.11-15</ispartof><rights>Copyright © 2016 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26790588$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rai, Bhavan Prasad</creatorcontrib><creatorcontrib>Baum, Richard Paul</creatorcontrib><creatorcontrib>Patel, Amit</creatorcontrib><creatorcontrib>Hughes, Robert</creatorcontrib><creatorcontrib>Alonzi, Roberto</creatorcontrib><creatorcontrib>Lane, Tim</creatorcontrib><creatorcontrib>Adshead, Jim</creatorcontrib><creatorcontrib>Vasdev, Nikhil</creatorcontrib><title>The Role of Positron Emission Tomography With (68)Gallium (Ga)-Labeled Prostate-specific Membrane Antigen (PSMA) in the Management of Patients With Organ-confined and Locally Advanced Prostate Cancer Prior to Radical Treatment and After Radical Prostatectomy</title><title>Urology (Ridgewood, N.J.)</title><addtitle>Urology</addtitle><description>The role of positron emission tomography (PET) with (68)Gallium (Ga)-labeled prostate-specific membrane antigen (PSMA) imaging for prostate cancer is gaining prominence. Current imaging strategies, despite having progressed significantly, have limitations, in particular their ability to diagnose metastatic lymph node involvement. Preliminary results of PET with (68)Ga-labeled PSMA have shown encouraging results, particularly in the recurrent prostate cancer setting. Furthermore, the ability of PET with (68)Ga-labeled PSMA of playing a dual diagnostic and therapeutic setting (theranostics) is currently being investigated as well. PET with (68)Ga-labeled PSMA certainly has a role to play in bridging some of the voids in contemporary prostate cancer imaging tools.</description><subject>Antigens, Surface</subject><subject>Gallium Radioisotopes</subject><subject>Glutamate Carboxypeptidase II</subject><subject>Humans</subject><subject>Male</subject><subject>Neoplasm Recurrence, Local - diagnostic imaging</subject><subject>Positron-Emission Tomography - methods</subject><subject>Preoperative Care</subject><subject>Prostatectomy</subject><subject>Prostatic Neoplasms - diagnostic imaging</subject><subject>Prostatic Neoplasms - pathology</subject><subject>Prostatic Neoplasms - surgery</subject><issn>1527-9995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNpNkU9r3DAQxd1ASdI0H6FljrsHu5JseaWjWdJtYZcs6YYcF1mWvQq25EpywN--yp-FnmaGee_9YCZJvmGUYYTLH8_Z5GxvuzkjCNMMkwwV7CK5xpSsUs45vUq-eP-MECrLcnWZXJFyxRFl7PrTxeGk4MH2CmwLe-t1cNbA3aC917E52MF2ToynGZ50OMGiZMuN6Hs9DbDYiGW6FbXqVQN7Z30QQaV-VFK3WsJODbUTRkFlgu6UgcX-z65agjYQInMnjOjUoEx4I4ugY-vfKfeuEyaV1rTaxGxhGthaGbEzVM2LMPI_IKxfZxdnbR0ECw-i0VELB6dEeMt_9VdtiKLz7myWwQ7z1-RzK3qvbj_qTfL48-6w_pVu7ze_19U2HQnGIcWNFDJv8poRVde4LAiuOaOEF4XiZcsJooTmhJGC14jWSjAiefRwmvOGCZbfJIv33NHZv5Py4RivLFXfxyPZyR8xw0VJGSpWUfr9QzrVg2qOo9ODcPPx_Lf8H06HnSc</recordid><startdate>201609</startdate><enddate>201609</enddate><creator>Rai, Bhavan Prasad</creator><creator>Baum, Richard Paul</creator><creator>Patel, Amit</creator><creator>Hughes, Robert</creator><creator>Alonzi, Roberto</creator><creator>Lane, Tim</creator><creator>Adshead, Jim</creator><creator>Vasdev, Nikhil</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201609</creationdate><title>The Role of Positron Emission Tomography With (68)Gallium (Ga)-Labeled Prostate-specific Membrane Antigen (PSMA) in the Management of Patients With Organ-confined and Locally Advanced Prostate Cancer Prior to Radical Treatment and After Radical Prostatectomy</title><author>Rai, Bhavan Prasad ; Baum, Richard Paul ; Patel, Amit ; Hughes, Robert ; Alonzi, Roberto ; Lane, Tim ; Adshead, Jim ; Vasdev, Nikhil</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p211t-1dcac3d3b82ebb16421b9852944e96f920525328249b05bea82c9dca9539d8a83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Antigens, Surface</topic><topic>Gallium Radioisotopes</topic><topic>Glutamate Carboxypeptidase II</topic><topic>Humans</topic><topic>Male</topic><topic>Neoplasm Recurrence, Local - diagnostic imaging</topic><topic>Positron-Emission Tomography - methods</topic><topic>Preoperative Care</topic><topic>Prostatectomy</topic><topic>Prostatic Neoplasms - diagnostic imaging</topic><topic>Prostatic Neoplasms - pathology</topic><topic>Prostatic Neoplasms - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rai, Bhavan Prasad</creatorcontrib><creatorcontrib>Baum, Richard Paul</creatorcontrib><creatorcontrib>Patel, Amit</creatorcontrib><creatorcontrib>Hughes, Robert</creatorcontrib><creatorcontrib>Alonzi, Roberto</creatorcontrib><creatorcontrib>Lane, Tim</creatorcontrib><creatorcontrib>Adshead, Jim</creatorcontrib><creatorcontrib>Vasdev, Nikhil</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Urology (Ridgewood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rai, Bhavan Prasad</au><au>Baum, Richard Paul</au><au>Patel, Amit</au><au>Hughes, Robert</au><au>Alonzi, Roberto</au><au>Lane, Tim</au><au>Adshead, Jim</au><au>Vasdev, Nikhil</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Role of Positron Emission Tomography With (68)Gallium (Ga)-Labeled Prostate-specific Membrane Antigen (PSMA) in the Management of Patients With Organ-confined and Locally Advanced Prostate Cancer Prior to Radical Treatment and After Radical Prostatectomy</atitle><jtitle>Urology (Ridgewood, N.J.)</jtitle><addtitle>Urology</addtitle><date>2016-09</date><risdate>2016</risdate><volume>95</volume><spage>11</spage><epage>15</epage><pages>11-15</pages><eissn>1527-9995</eissn><abstract>The role of positron emission tomography (PET) with (68)Gallium (Ga)-labeled prostate-specific membrane antigen (PSMA) imaging for prostate cancer is gaining prominence. Current imaging strategies, despite having progressed significantly, have limitations, in particular their ability to diagnose metastatic lymph node involvement. Preliminary results of PET with (68)Ga-labeled PSMA have shown encouraging results, particularly in the recurrent prostate cancer setting. Furthermore, the ability of PET with (68)Ga-labeled PSMA of playing a dual diagnostic and therapeutic setting (theranostics) is currently being investigated as well. PET with (68)Ga-labeled PSMA certainly has a role to play in bridging some of the voids in contemporary prostate cancer imaging tools.</abstract><cop>United States</cop><pmid>26790588</pmid><doi>10.1016/j.urology.2015.12.048</doi><tpages>5</tpages></addata></record>
fulltext fulltext
identifier EISSN: 1527-9995
ispartof Urology (Ridgewood, N.J.), 2016-09, Vol.95, p.11-15
issn 1527-9995
language eng
recordid cdi_proquest_miscellaneous_1814658047
source ScienceDirect Journals
subjects Antigens, Surface
Gallium Radioisotopes
Glutamate Carboxypeptidase II
Humans
Male
Neoplasm Recurrence, Local - diagnostic imaging
Positron-Emission Tomography - methods
Preoperative Care
Prostatectomy
Prostatic Neoplasms - diagnostic imaging
Prostatic Neoplasms - pathology
Prostatic Neoplasms - surgery
title The Role of Positron Emission Tomography With (68)Gallium (Ga)-Labeled Prostate-specific Membrane Antigen (PSMA) in the Management of Patients With Organ-confined and Locally Advanced Prostate Cancer Prior to Radical Treatment and After Radical Prostatectomy
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T21%3A31%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20Role%20of%20Positron%20Emission%20Tomography%20With%20(68)Gallium%20(Ga)-Labeled%20Prostate-specific%20Membrane%20Antigen%20(PSMA)%20in%20the%20Management%20of%20Patients%20With%20Organ-confined%20and%20Locally%20Advanced%20Prostate%20Cancer%20Prior%20to%20Radical%20Treatment%20and%20After%20Radical%20Prostatectomy&rft.jtitle=Urology%20(Ridgewood,%20N.J.)&rft.au=Rai,%20Bhavan%20Prasad&rft.date=2016-09&rft.volume=95&rft.spage=11&rft.epage=15&rft.pages=11-15&rft.eissn=1527-9995&rft_id=info:doi/10.1016/j.urology.2015.12.048&rft_dat=%3Cproquest_pubme%3E1814658047%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-p211t-1dcac3d3b82ebb16421b9852944e96f920525328249b05bea82c9dca9539d8a83%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1814658047&rft_id=info:pmid/26790588&rfr_iscdi=true