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7 tesla T2‐weighted MRI as a tool to improve detection of focal cortical dysplasia
Focal cortical dysplasia is one of the most common underlying pathologies in patients who undergo surgery for refractory epilepsy. Absence of a MRI‐visible lesion necessitates additional diagnostic tests and is a predictor of poor surgical outcome. We describe a series of six patients with refractor...
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Published in: | Epileptic disorders 2016-09, Vol.18 (3), p.315-323 |
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Main Authors: | , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that cite this one |
Online Access: | Get full text |
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Summary: | Focal cortical dysplasia is one of the most common underlying pathologies in patients who undergo surgery for refractory epilepsy. Absence of a MRI‐visible lesion necessitates additional diagnostic tests and is a predictor of poor surgical outcome. We describe a series of six patients with refractory epilepsy due to histopathologically‐confirmed focal cortical dysplasia, for whom pre‐surgical 7 tesla T2*‐weighted MRI was acquired. In four of six patients, T2* sequences showed areas of marked superficial hypointensity, co‐localizing with the epileptogenic lesion. 7 tesla T2* hypointensities overlying focal cortical dysplasia may represent leptomeningeal venous vascular abnormalities associated with the underlying dysplastic cortex. Adding T2* sequences to the MRI protocol may aid in the detection of focal cortical dysplasias. |
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ISSN: | 1294-9361 1950-6945 |
DOI: | 10.1684/epd.2016.0838 |