Pediatric myositis ossificans mimicking osteosarcoma

Myositis ossificans (MO) is a rare benign cause of heterotopic bone formation in soft tissue that most commonly affects young adults, typically following trauma. We report the case of an 11‐year‐old girl who developed MO mimicking osteosarcoma in her right shoulder. Plain radiography and computed to...

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Bibliographic Details
Published in:Pediatrics international 2015-10, Vol.57 (5), p.996-999
Main Authors: Yamaga, Kensaku, Kobayashi, Eisuke, Kubota, Daisuke, Setsu, Nokitaka, Tanaka, Yuya, Minami, Yusuke, Tanzawa, Yoshikazu, Nakatani, Fumihiko, Kawai, Akira, Chuman, Hirokazu
Format: Article
Language:English
Subjects:
Biopsy
Bone Neoplasms - diagnosis
Cancer
Child
Diagnosis, Differential
Diagnostic Errors
Female
Humans
humerus
Magnetic Resonance Imaging
myositis ossificans
Myositis Ossificans - diagnosis
osteosarcoma
Osteosarcoma - diagnosis
Pathology
Pediatrics
periosteal reaction
Tomography, X-Ray Computed
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Summary:Myositis ossificans (MO) is a rare benign cause of heterotopic bone formation in soft tissue that most commonly affects young adults, typically following trauma. We report the case of an 11‐year‐old girl who developed MO mimicking osteosarcoma in her right shoulder. Plain radiography and computed tomography showed poorly defined flocculated densities in the soft tissue and a periosteal reaction along the proximal humerus. On magnetic resonance imaging, the mass displayed an ill‐defined margin and inhomogeneous signal change. Histologically, the mass had a pseudosarcomatous appearance. Based on these findings, the patient was initially misdiagnosed with osteosarcoma at another hospital. The diagnosis was difficult because the patient was 11 years old and had no trauma history, with atypical radiographic changes and a predilection for the site of origin for osteosarcomas. We finally made the correct diagnosis of MO by carefully reviewing and reflecting on the pathological differences between stages.
ISSN:1328-8067
1442-200X
DOI:10.1111/ped.12672