Ultra-turrax based ultrasound-assisted extraction of five organic acids from honeysuckle (Lonicera japonica Thunb.) and optimization of extraction process

• Published in: Separation and purification technology 2016-06, Vol.166, p.73-82
• Main Authors: Xu, Wen-Jing, Zhai, Jia-Wen, Cui, Qi, Liu, Ju-Zhao, Luo, Meng, Fu, Yu-Jie, Zu, Yuan-Gang
• Format: Article
• Language: English
• Subjects: Ethyl alcohol; Extraction; Honeysuckle; Liquids; Lonicera japonica; Mass transfer; Mass transfer kinetics; Optimization; Organic acids; Particle size distribution; Purification; Ultra-turrax based ultrasound-assisted extraction; United Arab Emirates; Ute
• ISSN: 1383-5866; 1873-3794
• DOI: 10.1016/j.seppur.2016.04.003

[Display omitted] •Ultra-turrax based ultrasound-assisted extraction (UT-UAE) method was developed.•Efficient and fast UT-UAE of organic acids from honeysuckle was investigated.•UT-UAE with high extraction efficiency could be applied in industrial production. In the present study, a highly effective extraction method, namely ultra-turrax based ultrasound-assisted extraction (UT-UAE), was firstly designed to extract the main organic acids from honeysuckle. Single factor experiments and Box-Behnken design (BBD) were conducted to optimize the extraction process. The optimal extraction conditions were as follows: homogeneous rate 8000rpm, ultrasonic intensity 0.347W/cm2, ethanol concentration 65%, time 10min and liquid/solid ratio 20:1mL/g. Moreover, the mass transfer kinetics and particle size distribution were investigated in order to demonstrate the advantages of UT-UAE. Through the comparison with ultra-turrax extraction (UTE) and ultrasound-assisted extraction (UAE) methods, the proposed method exhibited higher yields of five target organic acids in a shorter time. The results showed that UT-UAE could be a promising method for fast extracting active compounds from plants.