Prostate cancer diagnosis by optical coherence tomography: First results from a needle based optical platform for tissue sampling

The diagnostic accuracy of Optical Coherence Tomography (OCT) based optical attenuation coefficient analysis is assessed for the detection of prostate cancer. Needle‐based OCT‐measurements were performed on the prostate specimens. Attenuation coefficients were determined by an earlier described in‐h...

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Bibliographic Details
Published in:Journal of biophotonics 2016-05, Vol.9 (5), p.490-498
Main Authors: Muller, Berrend G., de Bruin, Daniel M., Brandt, Martin J., van den Bos, Willemien, van Huystee, Suzanne, Faber, D. J., Savci, Dilaria, Zondervan, Patricia J., de Reijke, Theo M., Laguna-Pes, M. Pilar, van Leeuwen, Ton G., de la Rosette, Jean J. M. C. H.
Format: Article
Language:English
Subjects:
Attenuation coefficients
Cancer
Diagnosis
Humans
Imaging
Male
Needles
Optical Coherence Tomography
Patients
Prostate
Prostate cancer
Prostatic Neoplasms - diagnostic imaging
Sampling
Tomography, Optical Coherence
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Summary:The diagnostic accuracy of Optical Coherence Tomography (OCT) based optical attenuation coefficient analysis is assessed for the detection of prostate cancer. Needle‐based OCT‐measurements were performed on the prostate specimens. Attenuation coefficients were determined by an earlier described in‐house developed software package. The mean attenuation coefficients (benign OCT data; malignant OCT data; p‐value Mann‐Whitney U test) were: (3.56 mm–1; 3.85 mm–1; p 
ISSN:1864-063X
1864-0648
DOI:10.1002/jbio.201500252