Arabino mycolates from synthetic mycolic acids

The synthesis of single mono-arabino mycolates, important lipid antigens from mycobacteria is described, using structurally defined synthetic mycolic acids. Preliminary assays indicate that these are differentially antigenic to antibodies in the serum of people with active tuberculosis. [Display omi...

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Published in:Tetrahedron 2016-06, Vol.72 (22), p.2849-2857
Main Authors: Mohammed, Mohsin O., Baird, Mark S., Al Dulayymi, Juma'a R., Jones, Alison, Gwenin, Christopher D.
Format: Article
Language:English
Subjects:
Antibodies
Antigens
Arabino mycolates
Assaying
Lipids
Mycobacteria
Serums
Synthesis
Tetrahedrons
Tuberculosis
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cites cdi_FETCH-LOGICAL-c373t-f98c839079d33bee37bb6cb2e345acb2eba724370f524aa7ba59ab879b7978ae3
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container_issue 22
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creator Mohammed, Mohsin O.
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description The synthesis of single mono-arabino mycolates, important lipid antigens from mycobacteria is described, using structurally defined synthetic mycolic acids. Preliminary assays indicate that these are differentially antigenic to antibodies in the serum of people with active tuberculosis. [Display omitted]
doi_str_mv 10.1016/j.tet.2016.03.083
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subjects Antibodies
Antigens
Arabino mycolates
Assaying
Lipids
Mycobacteria
Serums
Synthesis
Tetrahedrons
Tuberculosis
title Arabino mycolates from synthetic mycolic acids
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