Effect of Bone Inhomogeneity on Tibiofemoral Contact Mechanics during Physiological Loading

Abstract It is not known how inhomogeneous mechanical properties of bone affect contact mechanics and cartilage response during physiological loading of the knee joint. In this study, a finite element model of a cadaver knee joint was constructed based on quantitative computed tomography (QCT). The...

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Bibliographic Details
Published in:Journal of biomechanics 2016-05, Vol.49 (7), p.1111-1120
Main Authors: Venäläinen, M S, Mononen, M E, Väänänen, S P, Jurvelin, J S, Töyräs, J, Virén, T, Korhonen, R K
Format: Article
Language:English
Subjects:
Articular cartilage
Biomechanical Phenomena
Bone
Bone density
Bone mineral density
Bones
Cartilage
Cartilage, Articular - diagnostic imaging
Cartilage, Articular - physiology
Conflicts of interest
Contact
Contact pressure
Contact stresses
Elastic Modulus
Elasticity
Femur - diagnostic imaging
Femur - physiology
Finite Element Analysis
Funding
Humans
Kinematics
Knee
Knee joint
Knee Joint - diagnostic imaging
Knee Joint - physiology
Male
Mechanics
Medical imaging
Osteoporosis
Physical Medicine and Rehabilitation
Physiology
Porosity
Pressure
Quantitative computed tomography
Software
Strain
Stress, Mechanical
Stresses
Tibia - diagnostic imaging
Tibia - physiology
Tomography
Tomography, X-Ray Computed
Weight-Bearing
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Summary:Abstract It is not known how inhomogeneous mechanical properties of bone affect contact mechanics and cartilage response during physiological loading of the knee joint. In this study, a finite element model of a cadaver knee joint was constructed based on quantitative computed tomography (QCT). The mechanical properties of bone were altered and their effect on tibiofemoral contact mechanics and cartilage stresses, strains and pore pressures were evaluated during the first 20% of stance. For this purpose, models with rigid, homogeneous and inhomogeneous bones were created. When bone was modeled to be rigid, the resulting contact pressures were substantially higher in the medial side of the joint, as compared to the non-rigid bones. Similar changes were revealed also in stresses, strains and pore pressures throughout the cartilage depth at the cartilage-cartilage contact area. Furthermore, the mechanical response of medial tibial cartilage was found to be highly dependent on the bone properties. When the Young’s modulus in the model with homogeneous bone was
ISSN:0021-9290
1873-2380
DOI:10.1016/j.jbiomech.2016.02.033