The association between ABO blood group and obstetric hemorrhage

• Published in: Journal of thrombosis and thrombolysis 2016-10, Vol.42 (3), p.340-345
• Main Authors: Drukker, Lior, Srebnik, Naama, Elstein, Deborah, Levitt, Lorinne, Samueloff, Arnon, Farkash, Rivka, Grisaru-Granovsky, Sorina, Sela, Hen Y.
• Format: Article
• Language: English
• Subjects: ABO Blood-Group System - physiology; Adult; Cardiology; Erythrocyte Transfusion - utilization; Female; Hematology; Hemoglobins - analysis; Humans; Medicine; Medicine & Public Health; Odds Ratio; Postpartum Hemorrhage - blood; Postpartum Hemorrhage - etiology; Postpartum Hemorrhage - immunology; Pregnancy; Retrospective Studies; Risk Factors
• ISSN: 0929-5305; 1573-742X
• DOI: 10.1007/s11239-016-1360-5

Whether intra- and early post-partum hemorrhage is influenced by ABO blood groups remains unknown. Therefore, we compared women with O to non-O blood groups with regard to maternal post-partum hemorrhage and transfusion need. This retrospective study was conducted in a single tertiary center between 2005 and 2014. For the purpose of the study, parturients were categorized as O and non-O blood groups. Data included all deliveries but excluded patients with missing blood grouping or hemoglobin values, and/or stillbirth. Drop in hemoglobin was defined as hemoglobin concentration at admission for delivery minus lowest hemoglobin concentration post-delivery. Study outcomes were postpartum hemorrhage, hemoglobin drop >2–7 g/dL inclusive, and packed red blood cells transfusion. Statistics: descriptive, χ 2 (p