Scaffolds and tissue regeneration: An overview of the functional properties of selected organic tissues

Tissue engineering plays a significant role both in the re-establishment of functions and regeneration of organic tissues. Success in manufacturing projects for biological scaffolds, for the purpose of tissue regeneration, is conditioned by the selection of parameters such as the biomaterial, the de...

Full description

Saved in:
Bibliographic Details
Published in:Journal of biomedical materials research. Part B, Applied biomaterials Applied biomaterials, 2016-10, Vol.104 (7), p.1483-1494
Main Authors: Rebelo, Márcia A., Alves, Thais F. R., de Lima, Renata, Oliveira Jr, José M., Vila, Marta M. D. C., Balcão, Victor M., Severino, Patrícia, Chaud, Marco V.
Format: Article
Language:English
Subjects:
Animals
biomaterial
Biomedical materials
biomimetic platform
Cell Proliferation
Extracellular Matrix - chemistry
Humans
Materials research
Materials science
quorum sensing
Regeneration
scaffold
Science & Technology
tissue regeneration
Tissue Scaffolds
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Tissue engineering plays a significant role both in the re-establishment of functions and regeneration of organic tissues. Success in manufacturing projects for biological scaffolds, for the purpose of tissue regeneration, is conditioned by the selection of parameters such as the biomaterial, the device architecture, and the specificities of the cells making up the organic tissue to create, in vivo, a microenvironment that preserves and further enhances the proliferation of a specific cell phenotype. To support this approach, we have screened scientific publications that show biomedical applications of scaffolds, biomechanical, morphological, biochemical, and hemodynamic characteristics of the target organic tissues, and the possible interactions between different cell matrices and biological scaffolds. This review article provides an overview on the biomedical application of scaffolds and on the characteristics of the (bio)materials commonly used for manufacturing these biological devices used in tissue engineering, taking into consideration the cellular specificity of the target tissue. Contract grant sponsor: FAPESP, Sao Paulo, Brazil; contract grant numbers: 2013/03181-6; 2013/19300-4Contract grant sponsor: FINEP Innovation and Research; contract grant number: 01.13.0286.00
ISSN:1552-4973
1552-4981
DOI:10.1002/jbm.b.33482