Could Ozone Be Used as a Feasible Future Treatment in Osteoarthritis of the Knee?

Osteoarthritis (OA) is one of the most disabling and incapacitating diseases on the autonomy of older people, affecting their quality of life. OA produces great impact on pain, function and use of resources, being considered as an important problem of Public Health. OA is a degenerative and progress...

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Bibliographic Details
Published in:Diversity and equality in health and care 2016-01, Vol.13 (3), p.232-239
Main Author: Fernandez Cuadros, Marcos Edgar
Format: Article
Language:English
Subjects:
Antioxidants
Arthritis
Autonomy
Bone marrow
Bones
Cartilage
Chronic illnesses
Cysts
Cytokines
Disease
Enzymes
Growth factors
Inflammation
Obesity
Older people
Osteoarthritis
Pain
Public health
Quality of life
Stem cells
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Summary:Osteoarthritis (OA) is one of the most disabling and incapacitating diseases on the autonomy of older people, affecting their quality of life. OA produces great impact on pain, function and use of resources, being considered as an important problem of Public Health. OA is a degenerative and progressive disease without treatment nowadays. The goals in OA treatment are to ameliorate symptoms and diminish articular damage. In knee OA, there is destruction of cartilage and subchondral bone, with the consequent narrowing of articular space. Knee OA is multifactorial. Besides the bio mechanic factors, trauma and obesity; it is believed that inflammation plays an important role. Future treatments should act on the regulation of inflammation to diminish progression of OA. There is evidence on several studies and years of experience that state that Ozone acts on the modulation of inflammation. The objective of this paper is to review the main pathophysiological mechanisms involved in knee OA, and to postulate ozone as a promising and ideal conservative treatment, since it could act on several therapeutic targets, besides inflammation.
ISSN:2049-5471
2049-5471
2049-548X
DOI:10.21767/2049-5471.100057