Evolution of RAG transposon unveiled

One hallmark of the adaptive immune system evolved from jawed vertebrates is the generation of a highly diversified repertoire of antigen receptors.RAG proteins are key recombinase in mammalian lymphoid cells.A recent study

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Bibliographic Details
Published in:Science China. Life sciences 2016-09, Vol.59 (9), p.968-970
Main Authors: Ding, Xiao, Dong, Chen
Format: Article
Language:English
Subjects:
Animals
Biomedical and Life Sciences
DNA Transposable Elements - genetics
DNA-Binding Proteins - genetics
Evolution, Molecular
Homeodomain Proteins - genetics
Insight
Lancelets - genetics
Life Sciences
Models, Genetic
Terminal Repeat Sequences - genetics
V(D)J Recombination - genetics
Vertebrates - genetics
哺乳动物
多样化
抗原蛋白
标志性
系统进化
脊椎动物
转座子
适应性
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Description
Summary:One hallmark of the adaptive immune system evolved from jawed vertebrates is the generation of a highly diversified repertoire of antigen receptors.RAG proteins are key recombinase in mammalian lymphoid cells.A recent study
ISSN:1674-7305
1869-1889
DOI:10.1007/s11427-016-5107-5