Efficacy and outcomes of continuous peritoneal dialysis versus daily intermittent hemodialysis in pediatric acute kidney injury

Background Acute kidney injury (AKI) requiring renal replacement therapy (RRT) is associated with high patient morbidity and mortality. There is no consensus on the best RRT modality for pediatric AKI. Methods The efficacy and safety of continuous peritoneal dialysis (cPD) and daily intermittent hem...

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Bibliographic Details
Published in:Pediatric nephrology (Berlin, West) West), 2016-10, Vol.31 (10), p.1681-1689
Main Authors: Basu, Biswanath, Mahapatra, Tapan Kumar Sinha, Roy, Birendranath, Schaefer, Franz
Format: Article
Language:English
Subjects:
Acute Kidney Injury - mortality
Acute Kidney Injury - therapy
Acute renal failure
Adolescent
Care and treatment
Catheters
Cause of Death
Child
Child, Preschool
Continuous ambulatory peritoneal dialysis
Dialysate
Disease Progression
Fatalities
Female
Hemodialysis
Hemodynamics
Humans
Infant
Kaplan-Meier Estimate
Kidney Failure, Chronic - mortality
Kidney Failure, Chronic - therapy
Kidney Function Tests
Kidneys
Male
Medicine
Medicine & Public Health
Mortality
Nephrology
Original Article
Patient outcomes
Patients
Pediatric research
Pediatrics
Peritoneal dialysis
Peritoneal Dialysis, Continuous Ambulatory - adverse effects
Peritoneal Dialysis, Continuous Ambulatory - methods
Peritoneal Dialysis, Continuous Ambulatory - mortality
Recovery of Function
Renal Dialysis - adverse effects
Renal Dialysis - methods
Renal Dialysis - mortality
Renal Replacement Therapy
Risk Factors
Survival Analysis
Treatment Outcome
Uremia
Uremia - therapy
Uremia - urine
Urinary Catheterization - adverse effects
Urology
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Summary:Background Acute kidney injury (AKI) requiring renal replacement therapy (RRT) is associated with high patient morbidity and mortality. There is no consensus on the best RRT modality for pediatric AKI. Methods The efficacy and safety of continuous peritoneal dialysis (cPD) and daily intermittent hemodialysis (dHD) were compared in 136 children aged 1 month to 16 years requiring RRT for AKI. Mortality, risk factors and causes of death, 1-month and 3-month renal recovery rates, and technique-related complications were assessed. Results Uremia control and the rate of catheter-related complications were comparable in the groups. Thirty-day survival was 60.7 % (51 out of 84) with cPD and 36.5 % (19 out of 52) with dHD ( p  = 0.019). Although age
ISSN:0931-041X
1432-198X
DOI:10.1007/s00467-016-3412-7