Clinical-radiologic correlation of mixed epithelial and stromal tumor of the kidneys: Cases analysis

Abstract Background Mixed epithelial and stromal tumor of the kidney (MESTK) is a rare tumor, with few malignant cases reported. Occurring mostly in middle-aged women, it is characterized by a biphasic pathological structure. Method This study retrospectively reviewed the imaging findings and medica...

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Bibliographic Details
Published in:Journal of the Chinese Medical Association 2016-10, Vol.79 (10), p.554-558
Main Authors: Tsai, Sheng-Han, Wang, Jia-Hwia, Lai, Yi-Chen, Chang, Yen-Hwa, Chung, Hsiao-Jen, Chang, Luke S
Format: Article
Language:English
Subjects:
Adult
Aged
Bosniak category
computed tomography
Female
Humans
Internal Medicine
Kidney - pathology
Kidney Neoplasms - diagnostic imaging
Kidney Neoplasms - surgery
Middle Aged
mixed epithelial and stromal tumor of the kidney
Neoplasms, Complex and Mixed - diagnostic imaging
Neoplasms, Complex and Mixed - surgery
Neoplasms, Glandular and Epithelial - diagnostic imaging
Neoplasms, Glandular and Epithelial - surgery
Nephrectomy
nephron-sparing surgery
Retrospective Studies
Tomography, X-Ray Computed
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Summary:Abstract Background Mixed epithelial and stromal tumor of the kidney (MESTK) is a rare tumor, with few malignant cases reported. Occurring mostly in middle-aged women, it is characterized by a biphasic pathological structure. Method This study retrospectively reviewed the imaging findings and medical records of six MESTK cases of a single institution in a 10-year period. Results All of the patients were middle-aged women without hormone therapy history. The typical image was a renal tumor with varied cystic components. Half of the cases had sinus invagination, but only one had intratumor calcification. On imaging studies, four were Bosniak Category IV, one was Category III, and one presented as a solid tumor. The mean RENAL nephrometry score was 9.3. Five patients underwent partial nephrectomy, with no statistical renal functional deterioration after nephron-sparing surgery. There were no peri-operative complications. Conclusion Surgery remains the treatment of choice for MESTK, and nephron-sparing surgery should be considered in feasible cases.
ISSN:1726-4901
1728-7731
1728-7731
DOI:10.1016/j.jcma.2016.02.012