Risk Factors of Nicardipine - Related Phlebitis in Acute Stroke Patients

Background and Purpose Intravenous nicardipine is generally used to treat hypertension in acute stroke patients but is associated with frequent phlebitis. We aimed to identify the incidence and risk factors of phlebitis in such patients. Methods The incidence and risk factors of phlebitis were inves...

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Bibliographic Details
Published in:Journal of stroke and cerebrovascular diseases 2016-10, Vol.25 (10), p.2513-2518
Main Authors: Kawada, Kei, MS, Ohta, Tsuyoshi, MD, PhD, Tanaka, Koudai, MS, Kadoguchi, Naoto, MS, PhD, Yamamoto, Souichi, BS, Morimoto, Masanori, MD, PhD
Format: Article
Language:English
Subjects:
acute stroke
Administration, Intravenous
Aged
Aged, 80 and over
Antihypertensive Agents - administration & dosage
Antihypertensive Agents - adverse effects
Cardiovascular
Dose-Response Relationship, Drug
Female
Humans
Hypertension - diagnosis
Hypertension - drug therapy
Hypertension - epidemiology
Incidence
Japan - epidemiology
Logistic Models
Male
Middle Aged
Multivariate Analysis
Neurology
nicardipine
Nicardipine - administration & dosage
Nicardipine - adverse effects
Odds Ratio
Phlebitis
Phlebitis - chemically induced
Phlebitis - diagnosis
Phlebitis - epidemiology
Retrospective Studies
risk factor
Risk Factors
Stroke - diagnosis
Stroke - epidemiology
Time Factors
Treatment Outcome
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Summary:Background and Purpose Intravenous nicardipine is generally used to treat hypertension in acute stroke patients but is associated with frequent phlebitis. We aimed to identify the incidence and risk factors of phlebitis in such patients. Methods The incidence and risk factors of phlebitis were investigated in 358 acute stroke patients from July 2014 to June 2015. Results In total, 138 patients received intravenous nicardipine. Of 45 (12.6%) phlebitis patients in 358 acute stroke patients, 42 (93.3%) were administered nicardipine, which was significantly associated with phlebitis occurrence ( P  
ISSN:1052-3057
1532-8511
DOI:10.1016/j.jstrokecerebrovasdis.2016.06.028