Body Mass Index (BMI) is Associated with the Therapeutic Response to Oral Rehydration Solution in Children with Postural Tachycardia Syndrome

• Published in: Pediatric cardiology 2016-10, Vol.37 (7), p.1313-1318
• Main Authors: Li, Hongxia, Wang, Yuli, Liu, Ping, Chen, Yonghong, Feng, Xueli, Tang, Chaoshu, Du, Junbao, Jin, Hongfang
• Format: Article
• Language: English
• Subjects: Blood Pressure; Body Mass Index; Cardiac Surgery; Cardiology; Child; Children's furniture; Heart beat; Heart Rate; Humans; Medicine; Medicine & Public Health; Original Article; Postural Orthostatic Tachycardia Syndrome; Rehydration Solutions; ROC Curve; Tachycardia; Vascular Surgery
• ISSN: 0172-0643; 1432-1971
• DOI: 10.1007/s00246-016-1436-1

We aimed to explore whether the body mass index (BMI) was associated with the therapeutic response to oral rehydration solution (ORS) in children with postural tachycardia syndrome (POTS). Fifty-four children diagnosed as having POTS were included in this study. Fifty-six healthy children served as the controls. Children with POTS were treated with ORS, and their treatment response was evaluated. The baseline BMI was obtained by measuring the height and weight. The Pearson correlation was made between the baseline BMI and change in heart rate from supine to upright (ΔHR) and between baseline BMI and symptom score change (post-treatment vs. pre-treatment) in the POTS group. The value of BMI in predicting the therapeutic response to ORS was assessed by analyses of the receiver operating characteristic (ROC) curve. The BMI in the POTS group was significantly lower than that in the control group (18.22 ± 3.23 vs. 20.62 ± 3.05 kg/m 2 , p   0.05), but symptom score was lower in responders than that in non-responders (1.52 ± 0.95 vs. 2.32 ± 1.22, p