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Aerobic biotransformation of 4-fluorocinnamic acid to 4-fluorobenzoic acid
The biotransformation of 4-fluorocinnamic acid (FCA) using non-acclimated industrial activated sludge was investigated. FCA is a common intermediate in organic synthesis, and it is often present in aqueous waste streams. Hence, the biotransformation reactions this compound undergoes when exposed to...
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| Published in: | Biodegradation (Dordrecht) 2001, Vol.12 (1), p.23-29 |
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| container_title | Biodegradation (Dordrecht) |
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| creator | FREITAS DOS SANTOS, Luisa M SPICQ, Arnaud NEW, Anthony P BIUNDO, Giuseppe Lo WOLFF, Jean-Claude EDWARDS, Andrew |
| description | The biotransformation of 4-fluorocinnamic acid (FCA) using non-acclimated industrial activated sludge was investigated. FCA is a common intermediate in organic synthesis, and it is often present in aqueous waste streams. Hence, the biotransformation reactions this compound undergoes when exposed to activated sludge micro-organisms should be understood before waste streams are sent to biological wastewater treatment plants (WWTPs). FCA biotransformation was monitored using a wide range of analytical techniques. These techniques were used to monitor not only FCA disappearance, but also the formation of degradation products, in order to propose the metabolic pathway. FCA was biotransformed to 4-fluorobenzoic acid via the formation of 4-fluoroacetophenone. The removal of FCA up to 200 mg L(-1) followed first order kinetics. The half-lives for removal of FCA from the test solutions supplied with 200 mg L(-1), 100 mg L(-1), and 50 mg L(-1) were 53, 18, and 5 hours respectively. |
| doi_str_mv | 10.1023/A:1011973824171 |
| format | article |
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FCA is a common intermediate in organic synthesis, and it is often present in aqueous waste streams. Hence, the biotransformation reactions this compound undergoes when exposed to activated sludge micro-organisms should be understood before waste streams are sent to biological wastewater treatment plants (WWTPs). FCA biotransformation was monitored using a wide range of analytical techniques. These techniques were used to monitor not only FCA disappearance, but also the formation of degradation products, in order to propose the metabolic pathway. FCA was biotransformed to 4-fluorobenzoic acid via the formation of 4-fluoroacetophenone. The removal of FCA up to 200 mg L(-1) followed first order kinetics. The half-lives for removal of FCA from the test solutions supplied with 200 mg L(-1), 100 mg L(-1), and 50 mg L(-1) were 53, 18, and 5 hours respectively.</description><identifier>ISSN: 0923-9820</identifier><identifier>EISSN: 1572-9729</identifier><identifier>DOI: 10.1023/A:1011973824171</identifier><identifier>PMID: 11693292</identifier><language>eng</language><publisher>Dordrecht: Springer</publisher><subject>Acids ; Activated sludge ; Aerobiosis ; Benzoates - metabolism ; Biodegradation, Environmental ; Biological and medical sciences ; Biological treatment of waters ; Biological wastewater treatment ; Biotechnology ; Biotransformation ; Chromatography, High Pressure Liquid ; Cinnamates - metabolism ; Degradation products ; Environment and pollution ; Fundamental and applied biological sciences. Psychology ; Gas Chromatography-Mass Spectrometry ; Industrial applications and implications. Economical aspects ; Industrial Waste ; Magnetic Resonance Spectroscopy ; Models, Chemical ; p-Fluorobenzoic acid ; p-Fluorocinnamic acid ; Sewage - microbiology ; Waste Disposal, Fluid ; Waste streams ; Wastewater treatment plants ; Water Pollutants, Chemical - metabolism ; Water treatment ; Water treatment plants</subject><ispartof>Biodegradation (Dordrecht), 2001, Vol.12 (1), p.23-29</ispartof><rights>2002 INIST-CNRS</rights><rights>Kluwer Academic Publishers 2001</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14140078$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11693292$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>FREITAS DOS SANTOS, Luisa M</creatorcontrib><creatorcontrib>SPICQ, Arnaud</creatorcontrib><creatorcontrib>NEW, Anthony P</creatorcontrib><creatorcontrib>BIUNDO, Giuseppe Lo</creatorcontrib><creatorcontrib>WOLFF, Jean-Claude</creatorcontrib><creatorcontrib>EDWARDS, Andrew</creatorcontrib><title>Aerobic biotransformation of 4-fluorocinnamic acid to 4-fluorobenzoic acid</title><title>Biodegradation (Dordrecht)</title><addtitle>Biodegradation</addtitle><description>The biotransformation of 4-fluorocinnamic acid (FCA) using non-acclimated industrial activated sludge was investigated. FCA is a common intermediate in organic synthesis, and it is often present in aqueous waste streams. Hence, the biotransformation reactions this compound undergoes when exposed to activated sludge micro-organisms should be understood before waste streams are sent to biological wastewater treatment plants (WWTPs). FCA biotransformation was monitored using a wide range of analytical techniques. These techniques were used to monitor not only FCA disappearance, but also the formation of degradation products, in order to propose the metabolic pathway. FCA was biotransformed to 4-fluorobenzoic acid via the formation of 4-fluoroacetophenone. The removal of FCA up to 200 mg L(-1) followed first order kinetics. 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Economical aspects</subject><subject>Industrial Waste</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>Models, Chemical</subject><subject>p-Fluorobenzoic acid</subject><subject>p-Fluorocinnamic acid</subject><subject>Sewage - microbiology</subject><subject>Waste Disposal, Fluid</subject><subject>Waste streams</subject><subject>Wastewater treatment plants</subject><subject>Water Pollutants, Chemical - metabolism</subject><subject>Water treatment</subject><subject>Water treatment plants</subject><issn>0923-9820</issn><issn>1572-9729</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><recordid>eNqF0E1LxDAQBuAgiq6rZ2-yCHqrzuSjabwti58seNFzSdIEsrTN2rQH_fVWrApePA3MPAwzLyEnCJcIlF0trxEQlWQF5Shxh8xQSJopSdUumYGiLFMFhQNymNIGAJQEuk8OEHPFqKIz8rh0XTTBLkyIfafb5GPX6D7EdhH9gme-HmIXbWhb3YxK21At-vgzMK59j1P_iOx5XSd3PNU5ebm9eV7dZ-unu4fVcp1tGc37zChfiSLX3kjrlBDOaeENuPEiJSTa3AEwq4Tj2vnKcCgY5MgkNcJZBM_m5OJr77aLr4NLfdmEZF1d69bFIZVYUCa5wv8hzwELxkZ49gdu4tC14xOl5KxASfFz2-mEBtO4qtx2odHdW_md5QjOJ6CT1bUf07Qh_TqOHEAW7ANRcIHf</recordid><startdate>2001</startdate><enddate>2001</enddate><creator>FREITAS DOS SANTOS, Luisa M</creator><creator>SPICQ, Arnaud</creator><creator>NEW, Anthony P</creator><creator>BIUNDO, Giuseppe Lo</creator><creator>WOLFF, Jean-Claude</creator><creator>EDWARDS, Andrew</creator><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7QL</scope><scope>7ST</scope><scope>7T7</scope><scope>7UA</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BKSAR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>F1W</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H97</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>L.G</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PCBAR</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>SOI</scope></search><sort><creationdate>2001</creationdate><title>Aerobic biotransformation of 4-fluorocinnamic acid to 4-fluorobenzoic acid</title><author>FREITAS DOS SANTOS, Luisa M ; SPICQ, Arnaud ; NEW, Anthony P ; BIUNDO, Giuseppe Lo ; WOLFF, Jean-Claude ; EDWARDS, Andrew</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p326t-b9fd586afb7ce955eea5fb0e6939571c6e003c95e4aefdb4083061372b5ec10f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Acids</topic><topic>Activated sludge</topic><topic>Aerobiosis</topic><topic>Benzoates - metabolism</topic><topic>Biodegradation, Environmental</topic><topic>Biological and medical sciences</topic><topic>Biological treatment of waters</topic><topic>Biological wastewater treatment</topic><topic>Biotechnology</topic><topic>Biotransformation</topic><topic>Chromatography, High Pressure Liquid</topic><topic>Cinnamates - metabolism</topic><topic>Degradation products</topic><topic>Environment and pollution</topic><topic>Fundamental and applied biological sciences. 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| ispartof | Biodegradation (Dordrecht), 2001, Vol.12 (1), p.23-29 |
| issn | 0923-9820 1572-9729 |
| language | eng |
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| source | Springer Nature |
| subjects | Acids Activated sludge Aerobiosis Benzoates - metabolism Biodegradation, Environmental Biological and medical sciences Biological treatment of waters Biological wastewater treatment Biotechnology Biotransformation Chromatography, High Pressure Liquid Cinnamates - metabolism Degradation products Environment and pollution Fundamental and applied biological sciences. Psychology Gas Chromatography-Mass Spectrometry Industrial applications and implications. Economical aspects Industrial Waste Magnetic Resonance Spectroscopy Models, Chemical p-Fluorobenzoic acid p-Fluorocinnamic acid Sewage - microbiology Waste Disposal, Fluid Waste streams Wastewater treatment plants Water Pollutants, Chemical - metabolism Water treatment Water treatment plants |
| title | Aerobic biotransformation of 4-fluorocinnamic acid to 4-fluorobenzoic acid |
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