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How can we improve outcomes of chlamydia control programmes?

In Denmark, the incidence of gonorrhoea has been declining for years so gonococcal infection is not a likely candidate.6 However, Mycoplasma genitalium or ascendance of bacteria associated with bacterial vaginosis could be other candidates.7 But could the excess pelvic inflammatory disease risk asso...

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Published in:The Lancet infectious diseases 2016-09, Vol.16 (9), p.989-990
Main Authors: Schachter, Julius, Chow, Joan M
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Language:English
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description In Denmark, the incidence of gonorrhoea has been declining for years so gonococcal infection is not a likely candidate.6 However, Mycoplasma genitalium or ascendance of bacteria associated with bacterial vaginosis could be other candidates.7 But could the excess pelvic inflammatory disease risk associated with chlamydia infection still be due to chlamydia infection despite its having been diagnosed and treated? Antigen detection methods used during 1995-2000 could have missed 50% of infections detectable by second-generation nucleic acid amplification tests available afterwards.9,10 Patients with pelvic inflammatory disease were once routinely admitted to hospital and diagnosis of ectopic pregnancy was determined surgically, but both transitioned predominantly to outpatient management.11 Because ascertainment of complications was based solely on hospital records, further work is needed to see if cohort members attended other primary care settings for milder presentations of complications.
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Antigen detection methods used during 1995-2000 could have missed 50% of infections detectable by second-generation nucleic acid amplification tests available afterwards.9,10 Patients with pelvic inflammatory disease were once routinely admitted to hospital and diagnosis of ectopic pregnancy was determined surgically, but both transitioned predominantly to outpatient management.11 Because ascertainment of complications was based solely on hospital records, further work is needed to see if cohort members attended other primary care settings for milder presentations of complications.</description><identifier>ISSN: 1473-3099</identifier><identifier>EISSN: 1474-4457</identifier><identifier>DOI: 10.1016/S1473-3099(16)30131-1</identifier><identifier>PMID: 27289390</identifier><identifier>CODEN: LANCAO</identifier><language>eng</language><publisher>United States: Elsevier Ltd</publisher><subject>Bacterial infections ; Chlamydia ; Chlamydia Infections ; Chlamydia trachomatis ; Diagnostic tests ; Disease ; Health risks ; Hospitals ; Humans ; Infections ; Infectious Disease ; Infectious diseases ; Infertility ; Inflammatory diseases ; Mass Screening ; Nucleic acids ; Pregnancy complications ; Sexually transmitted diseases ; STD ; Womens health</subject><ispartof>The Lancet infectious diseases, 2016-09, Vol.16 (9), p.989-990</ispartof><rights>Schachter et al. 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subjects Bacterial infections
Chlamydia
Chlamydia Infections
Chlamydia trachomatis
Diagnostic tests
Disease
Health risks
Hospitals
Humans
Infections
Infectious Disease
Infectious diseases
Infertility
Inflammatory diseases
Mass Screening
Nucleic acids
Pregnancy complications
Sexually transmitted diseases
STD
Womens health
title How can we improve outcomes of chlamydia control programmes?
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