Organs-on-chips and Its Applications

Microfluidic chips have been proven to be attractive platforms for cell culture in vitro. Microfluidic chip-based organs-on-chips technology has received more attention because it can mimic the complex structures and functions of human organs. In this review, the recent advances of organs-on-chips t...

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Bibliographic Details
Published in:Fēnxī huàxué 2016-04, Vol.44 (4), p.533-541
Main Authors: SUNa, Wei, CHENa, Yu-Qing, LUOb, Guo-An, ZHANGc, Min, ZHANGa, Hong-Yang, WANGa, Yue-Rong, HUa, Ping
Format: Article
Language:English
Subjects:
Biotechnology
Construction
Human
Microfluidics
Organs
Platforms
Toxicology
Trends
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Summary:Microfluidic chips have been proven to be attractive platforms for cell culture in vitro. Microfluidic chip-based organs-on-chips technology has received more attention because it can mimic the complex structures and functions of human organs. In this review, the recent advances of organs-on-chips technology in different organs are introduced, including the build of human physiological models, drug discovery, and toxicology research. The development trend of this technology is also proposed.
ISSN:0253-3820
DOI:10.1016/S1872-2040(16)60920-9