Synthetic studies toward tetrapetalone A: attempted palladium π-allyl cascades toward a fused tricyclic intermediate

Efforts to install the core azepine ring in tetrapetalone A via a palladium π-allyl cascade reaction failed due to competing pathways that included an unexpected and interesting TMM-like cycloaddition reaction that delivers a complex tricyclic ring system. [Display omitted]

Saved in:
Bibliographic Details
Published in:Tetrahedron 2016-06, Vol.72 (26), p.3673-3677
Main Authors: Dhanjee, Heemal H., Haley, Matthew W., McMahon, Travis C., Buergler, Jonas F., Howell, Jennifer M., Kobayashi, Yutaka, Fujiwara, Koichi, Wood, John L.
Format: Article
Language:English
Subjects:
Cascade
Cascade chemical reactions
Cascades
Cycloaddition
Heterocycle
Palladium
Pathways
Pi-Allyl
Tetrahedrons
Tetrapetalone
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Efforts to install the core azepine ring in tetrapetalone A via a palladium π-allyl cascade reaction failed due to competing pathways that included an unexpected and interesting TMM-like cycloaddition reaction that delivers a complex tricyclic ring system. [Display omitted]
ISSN:0040-4020
1464-5416
DOI:10.1016/j.tet.2016.03.011